Biofilms in chronic wound infections: innovative antimicrobial approaches using the in vitro Lubbock chronic wound biofilm model

F Diban, S Di Lodovico, P Di Fermo, S D'Ercole… - International journal of …, 2023 - mdpi.com
Chronic wounds have harmful effects on both patients and healthcare systems. Wound
chronicity is attributed to an impaired healing process due to several host and local factors …

Recent Advances and Opportunities in the Study of Candida albicans Polymicrobial Biofilms

CH Pohl - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
It is well known that the opportunistic pathogenic yeast, Candida albicans, can form
polymicrobial biofilms with a variety of bacteria, both in vitro and in vivo, and that these …

Antimicrobial combined action of graphene oxide and light emitting diodes for chronic wound management

S Di Lodovico, F Diban, P Di Fermo, M Petrini… - International Journal of …, 2022 - mdpi.com
Innovative non-antibiotic compounds such as graphene oxide (GO) and light-emitting diodes
(LEDs) may represent a valid strategy for managing chronic wound infections related to …

Current and prospective therapeutic strategies: tackling Candida albicans and Streptococcus mutans cross-kingdom biofilm

Y Li, S Huang, J Du, M Wu, X Huang - Frontiers in Cellular and …, 2023 - frontiersin.org
Candida albicans (C. albicans) is the most frequent strain associated with cross-kingdom
infections in the oral cavity. Clinical evidence shows the co-existence of Streptococcus …

[HTML][HTML] Important challenges to finding new leads for new antibiotics

MA Farha, MM Tu, ED Brown - Current Opinion in Microbiology, 2025 - Elsevier
Identification of new antibiotics remains a huge challenge. The last antibiotic of new
chemical class and mechanism was discovered more than 30 years ago. Advances since …

[HTML][HTML] Staphylococcus pseudintermedius and Pseudomonas aeruginosa Lubbock Chronic Wound Biofilm (LCWB): a suitable dual-species model for in vitro studies

S Di Lodovico, M Petrini, P Di Fermo… - Microbes and …, 2024 - Elsevier
Antimicrobial treatment of methicillin-resistant Staphylococcus pseudintermedius associated
with canine wounds represents an important challenge. The aim of this study was to create a …

Novel arginine-and proline-rich candidacidal peptides obtained through a bioinformatic approach

T Ciociola, L Giovati, T De Simone, G Bergamaschi… - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance is a major public health concern worldwide. Albeit to a lesser extent
than bacteria, fungi are also becoming increasingly resistant to antifungal drugs. Moreover …

A Comprehensive Review of Recent Research into the Effects of Antimicrobial Peptides on Biofilms—January 2020 to September 2023

A Fontanot, I Ellinger, WWJ Unger, JP Hays - Antibiotics, 2024 - mdpi.com
Microbial biofilm formation creates a persistent and resistant environment in which
microorganisms can survive, contributing to antibiotic resistance and chronic inflammatory …