Occlusive arterial disease is a leading cause of morbidity and mortality worldwide. Aside
from balloon angioplasty, bypass graft surgery is the most commonly performed …

Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively
studied CC chemokine, and the amount of studies on its role in the etiologies of obesity-and …

Monocyte chemotactic protein-1 (MCP-1)(also referred to as chemokine (CC motif) ligand 2
(CCL2) is expressed by mainly inflammatory cells and endothelial cells. The expression …

The primary graft-related complication during the first clinical trial evaluating the use of
tissue-engineered vascular grafts (TEVGs) was stenosis. We investigated the role of …

RA is characterized by a systemic inflammatory state, in which immune cells and soluble
mediators play a crucial role. These inflammatory processes resemble those in other chronic …

Background and Purpose—Recent studies have suggested that chronic inflammation
actively participates in cerebral aneurysm (CA) formation. Macrophages accumulate in CA …

Vascular remodeling stands for structural changes of the vessel wall in response to various
noxious stimuli, which results in reorganization of the vessel wall architecture. Luminal …

The development of varicose veins or chronic venous insufficiency is preceded by and
associated with the pathophysiological remodelling of the venous wall. Recent work …

There is increasing recognition of an important contribution of chemokines and their
receptors in the pathology of atherosclerosis and related cardiovascular disease. The …

After the creation of an autogenous lower extremity bypass graft, the vein must undergo a
series of dynamic structural changes to stabilize the arterial hemodynamic forces. These …