Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …

Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

The expression of the reverse transsulfuration enzyme cystathionine-β-synthase (CBS) is
markedly increased in many forms of cancer, including colorectal, ovarian, lung, breast and …

Diabetic wounds are more likely to develop into complex and severe chronic wounds. The
objective of this study is to develop and assess a reactive oxygen species (ROS)‐responsive …

Resveratrol is an organic compound widely studied for its therapeutic uses. We investigated
whether resveratrol exerts cardioprotective effects by inhibiting ferroptosis via the Sirt1/p53 …

Tubular injury has been shown to play a critical role in the morbidity of diabetic kidney
disease (DKD); ferroptosis often occurs in tubules during renal disease development. This …

The past few decades have witnessed significant progress in the discovery of hydrogen
sulfide (H 2 S) as a ubiquitous gaseous signaling molecule in mammalian physiology, akin …

Hydrogen Sulfide (H2S), an endogenously produced gasotransmitter, is involved in various
important physiological and disease conditions, including vasodilation, stimulation of …

Fibrosis, which is characterized by excessive extracellular matrix (ECM) deposition, is a
wound-healing response to organ injury and may promote cancer and failure in various …

Increasing evidence supports a role of proximal tubular (PT) injury in the progression of
diabetic kidney disease (DKD), in patients with or without proteinuria. Research on the …