The emergence and spread of infectious diseases with pandemic potential occurred
regularly throughout history. Major pandemics and epidemics such as plague, cholera, flu …

Vector-borne diseases (VBDs) such as malaria, dengue, and leishmaniasis exert a huge
burden of morbidity and mortality worldwide, particularly affecting the poorest of the poor …

Executive summary 50 years after a noble but flawed attempt to eradicate malaria in the mid-
20th century, the global malaria community is once again seriously considering eradication …

Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …

Small laboratory cage trials of non-drive and gene-drive strains of the Asian malaria vector
mosquito, Anopheles stephensi, were used to investigate release ratios and other strain …

Gene drive technology offers the promise for a high-impact, cost-effective, and durable
method to control malaria transmission that would make a significant contribution to …

Every year, malaria kills approximately 405,000 people in Sub-Saharan Africa, most of them
children under the age of five years. In many countries, progress in malaria control has been …

Gene drives are a promising means of malaria control with the potential to cause sustained
reductions in transmission. In real environments, however, their impacts will depend on local …

Mosquitoes containing gene drive systems are being developed as complementary tools to
prevent transmission of malaria and other mosquito-borne diseases. As with any new tool …

New tools and advanced technologies have played key roles in facilitating basic research in
plant pathology and practical approaches for disease management and crop health …