Signal peptides (SP) are short peptides located in the N-terminal of proteins, carrying
information for protein secretion. They are ubiquitous to all prokaryotes and eukaryotes. SPs …

Lactobacilli belong to the lactic acid bacteria, which play a key role in industrial and artisan
food raw-material fermentation, including a large variety of fermented dairy products. Next to …

Microplastics (MPs) are increasingly entering the urban aquatic ecosystems, and the
environmental significance and health risks of plastisphere, a special biofilm on MPs, have …

The biotechnology industry has become a key element in modern societies. Within this
industry, the production of recombinant enzymes and biopharmaceutical proteins is of major …

Leptospirosis is one of the most common zoonotic diseases in the world, resulting in high
morbidity and mortality in humans and affecting global livestock production. Most infections …

The gram-positive bacterium Staphylococcus aureus is a frequent component of the human
microbial flora that can turn into a dangerous pathogen. As such, this organism is capable of …

Motivation: Computational prediction of signal peptides is of great importance in
computational biology. In addition to the general secretory pathway (Sec), Bacteria, Archaea …

Correct protein compartmentalization is a key step for molecular function and cell viability,
and this is especially true for membrane and externalized proteins of bacteria. Recent …

Surface proteins are critical in determining the identifying characteristics of individual
bacteria and their interaction with the environment. Because the structure of the cell surface …

Signal peptide-driven secretion of precursor proteins directs polypeptides across the plasma
membrane of bacteria. Two pathways, Sec-and SRP-dependent, converge at the SecYEG …