[HTML][HTML] SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development

S Zhou, P Lv, M Li, Z Chen, H Xin, S Reilly… - Biomedicine & …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating
global pandemic, which has seriously affected human health worldwide. The discovery of …

SARS-CoV-2 diagnostics based on nucleic acids amplification: from fundamental concepts to applications and beyond

JM Vindeirinho, E Pinho, NF Azevedo… - Frontiers in cellular and …, 2022 - frontiersin.org
COVID-19 pandemic ignited the development of countless molecular methods for the
diagnosis of SARS-CoV-2 based either on nucleic acid, or protein analysis, with the first …

Mutational insights into the envelope protein of SARS-CoV-2

MS Rahman, MN Hoque, MR Islam, I Islam, ID Mishu… - Gene reports, 2021 - Elsevier
The ongoing mutations in the structural proteins of SARS-CoV-2 are the major impediment
for prevention and control of the COVID-19 disease. Presently we focused on evolution of …

[HTML][HTML] A unique view of SARS-CoV-2 through the lens of ORF8 protein

SS Hassan, AAA Aljabali, PK Panda, S Ghosh… - Computers in biology …, 2021 - Elsevier
Immune evasion is one of the unique characteristics of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) attributed to its ORF8 protein. This protein modulates the …

[HTML][HTML] Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis

F De Maio, EL Cascio, G Babini, M Sali… - Microbes and …, 2020 - Elsevier
The Envelope (E) protein of SARS-CoV-2 is the most enigmatic protein among the four
structural ones. Most of its current knowledge is based on the direct comparison to the SARS …

Comparing the binding properties of peptides mimicking the Envelope protein of SARS‐CoV and SARS‐CoV‐2 to the PDZ domain of the tight junction‐associated …

A Toto, S Ma, F Malagrinò, L Visconti, L Pagano… - Protein …, 2020 - Wiley Online Library
The Envelope protein (E) is one of the four structural proteins encoded by the genome of
SARS‐CoV and SARS‐CoV‐2 Coronaviruses. It is an integral membrane protein, highly …

The pathophysiology, diagnosis and treatment of corona virus disease 2019 (COVID-19)

SK Das - Indian Journal of Clinical Biochemistry, 2020 - Springer
Since the beginning of this century, beta coronaviruses (CoV) have caused three zoonotic
outbreaks. However, little is currently known about the biology of the newly emerged SARS …

[HTML][HTML] Genome composition and genetic characterization of SARS-CoV-2

AM Al-Qaaneh, T Alshammari, R Aldahhan… - Saudi journal of …, 2021 - Elsevier
SARS-CoV-2 is a type of Betacoronaviruses responsible for COVID-19 pandemic disease,
with more than 1.745 million fatalities globally as of December-2020. Genetically, it is …

Genetic spectrum and distinct evolution patterns of SARS-CoV-2

S Liu, J Shen, S Fang, K Li, J Liu, L Yang… - Frontiers in …, 2020 - frontiersin.org
Four signature groups of frequently occurred single-nucleotide variants (SNVs) were
identified in over twenty-eight thousand high-quality and high-coverage SARS-CoV-2 …

SARS-CoV-2 infection: host response, immunity, and therapeutic targets

P Shivshankar, H Karmouty-Quintana, T Mills… - Inflammation, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic with …