Increasing the potency of MHC class II-presented epitopes by linkage to Ii-Key peptide
RE Humphreys, S Adams, G Koldzic, B Nedelescu… - Vaccine, 2000 - Elsevier
We previously found that peptide Ii77-92 from the immunoregulatory Ii protein significantly
enhances the binding of antigenic peptides to MHC class II molecules. Now a series of …
enhances the binding of antigenic peptides to MHC class II molecules. Now a series of …
MHC class II allosteric site drugs: new immunotherapeutics for malignant, infectious and autoimmune diseases
M Xu, J Li, JV Gulfo, E Von Hofe… - … Journal of Immunology, 2001 - Wiley Online Library
The discovery of the interactions of the 'Ii‐Key'segment of the Ii protein with the major
histocmpatibility complex (MHC) Class II allosteric site, which is adjacent to the antigenic …
histocmpatibility complex (MHC) Class II allosteric site, which is adjacent to the antigenic …