A review on locomotor training after spinal cord injury: reorganization of spinal neuronal circuits and recovery of motor function

AC Smith, M Knikou - Neural plasticity, 2016 - Wiley Online Library
Locomotor training is a classic rehabilitation approach utilized with the aim of improving
sensorimotor function and walking ability in people with spinal cord injury (SCI). Recent …

More than at the neuromuscular synapse: actions of botulinum neurotoxin A in the central nervous system

R Mazzocchio, M Caleo - The Neuroscientist, 2015 - journals.sagepub.com
Botulinum neurotoxin type A (BoNT/A) is a metalloprotease that produces a sustained yet
transitory blockade of transmitter release from peripheral nerve terminals. Local delivery of …

The effects of anodal transcranial direct current stimulation and patterned electrical stimulation on spinal inhibitory interneurons and motor function in patients with …

T Yamaguchi, T Fujiwara, YA Tsai, SC Tang… - Experimental brain …, 2016 - Springer
Supraspinal excitability and sensory input may play an important role for the modulation of
spinal inhibitory interneurons and functional recovery among patients with incomplete spinal …

Locomotor training improves premotoneuronal control after chronic spinal cord injury

M Knikou, CK Mummidisetty - Journal of neurophysiology, 2014 - journals.physiology.org
Spinal inhibition is significantly reduced after spinal cord injury (SCI) in humans. In this work,
we examined if locomotor training can improve spinal inhibition exerted at a presynaptic …

Co-contraction of ankle muscle activity during quiet standing in individuals with incomplete spinal cord injury is associated with postural instability

KL Fok, JW Lee, J Unger, K Chan, KE Musselman… - Scientific Reports, 2021 - nature.com
Previous findings indicate that co-contractions of plantarflexors and dorsiflexors during quiet
standing increase the ankle mechanical joint stiffness, resulting in increased postural sway …

Impaired corticomuscular coherence during isometric elbow flexion contractions in humans with cervical spinal cord injury

S Cremoux, J Tallet, F Dal Maso… - European Journal of …, 2017 - Wiley Online Library
After spinal cord injury (SCI), the reorganization of the neuromuscular system leads to
increased antagonist muscles' co‐activation—that is, increased antagonist vs. agonist …

Plasticity of corticospinal neural control after locomotor training in human spinal cord injury

M Knikou - Neural plasticity, 2012 - Wiley Online Library
Spinal lesions substantially impair ambulation, occur generally in young and otherwise
healthy individuals, and result in devastating effects on quality of life. Restoration of …

Restoring walking after spinal cord injury: operant conditioning of spinal reflexes can help

AK Thompson, JR Wolpaw - The Neuroscientist, 2015 - journals.sagepub.com
People with incomplete spinal cord injury (SCI) frequently suffer motor disabilities due to
spasticity and poor muscle control, even after conventional therapy. Abnormal spinal reflex …

Modulation of soleus stretch reflexes during walking in people with chronic incomplete spinal cord injury

AK Thompson, N Mrachacz-Kersting, T Sinkjær… - Experimental brain …, 2019 - Springer
In people with spasticity due to chronic incomplete spinal cord injury (SCI), it has been
presumed that the abnormal stretch reflex activity impairs gait. However, locomotor stretch …

Functional reorganization of soleus H-reflex modulation during stepping after robotic-assisted step training in people with complete and incomplete spinal cord injury

M Knikou - Experimental Brain Research, 2013 - Springer
Body weight–supported (BWS) robotic-assisted step training on a motorized treadmill is
utilized with the aim to improve walking ability in people after damage to the spinal cord …