[HTML][HTML] Delivery of nucleic acids using nanomaterials

Y Qin, L Ou, L Zha, Y Zeng, L Li - Molecular Biomedicine, 2023 - Springer
The increasing number of approved nucleic acid therapeutics demonstrates the potential for
the prevention and treatment of a broad spectrum of diseases. This trend underscores the …

[HTML][HTML] A Novel Transgenic Mouse Model Implicates Sirt2 as a Promoter of Hepatocellular Carcinoma

AV Schmidt, SP Monga, EV Prochownik… - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer deaths globally.
Incidence rates are steadily increasing, creating an unmet need for new therapeutic options …

Strategies for Improved pDNA Loading and Protection Using Cationic and Neutral LNPs with Industrial Scalability Potential Using Microfluidic Technology

I Ottonelli, E Adani, A Bighinati, S Cuoghi… - International Journal …, 2024 - Taylor & Francis
Purpose In recent years, microfluidic technologies have become mainstream in producing
gene therapy nanomedicines (NMeds) following the Covid-19 vaccine; however, extensive …