2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

Pulmonary hypertension associated with lung disease: new insights into pathomechanisms, diagnosis, and management

KM Olsson, TJ Corte, JC Kamp, D Montani… - The Lancet …, 2023 - thelancet.com
Patients with chronic lung diseases, particularly interstitial lung disease and chronic
obstructive pulmonary disease, frequently develop pulmonary hypertension, which results in …

[HTML][HTML] Phenotyping of idiopathic pulmonary arterial hypertension: a registry analysis

MM Hoeper, K Dwivedi, C Pausch… - The Lancet …, 2022 - thelancet.com
Background Among patients meeting diagnostic criteria for idiopathic pulmonary arterial
hypertension (IPAH), there is an emerging lung phenotype characterised by a low diffusion …

[HTML][HTML] Idiopathic pulmonary arterial hypertension phenotypes determined by cluster analysis from the COMPERA registry

MM Hoeper, C Pausch, E Grünig, H Klose… - The Journal of Heart and …, 2020 - Elsevier
The term idiopathic pulmonary arterial hypertension (IPAH) is used to categorize patients
with pre-capillary pulmonary hypertension of unknown origin. There is considerable …

The evolving landscape of pulmonary arterial hypertension clinical trials

J Weatherald, A Boucly, A Peters, D Montani, K Prasad… - The Lancet, 2022 - thelancet.com
Although it is a rare disease, the number of available therapeutic options for treating
pulmonary arterial hypertension has increased since the late 1990s, with multiple drugs …

Treatment of pulmonary arterial hypertension: recent progress and a look to the future

M Humbert, O Sitbon, C Guignabert… - The Lancet …, 2023 - thelancet.com
Pulmonary arterial hypertension (PAH) is a severe but treatable form of pre-capillary
pulmonary hypertension caused by pulmonary vascular remodelling. As a result of basic …

Pulmonary hypertension: a contemporary review

S Johnson, N Sommer, K Cox-Flaherty… - American journal of …, 2023 - atsjournals.org
Major advances in pulmonary arterial hypertension, pulmonary hypertension (PH)
associated with lung disease, and chronic thromboembolic PH cast new light on the …

The 6-min walk test as a primary end-point in interstitial lung disease

S Harari, AU Wells, WA Wuyts… - European …, 2022 - Eur Respiratory Soc
There is a need for clinical trial end-points to better assess how patients feel and function, so
that interventions can be developed which alleviate symptoms and improve quality of life …

Long‐term outcomes in patients with connective tissue disease–associated pulmonary arterial hypertension in the modern treatment era: meta‐analyses of …

D Khanna, C Zhao, R Saggar, SC Mathai… - Arthritis & …, 2021 - Wiley Online Library
Objective Data on the magnitude of benefit of modern therapies for pulmonary arterial
hypertension (PAH) in connective tissue disease (CTD)–associated PAH are limited. In this …

Pulmonary hypertension in interstitial lung disease: screening, diagnosis and treatment

J Behr, SD Nathan - Current Opinion in Pulmonary Medicine, 2021 - journals.lww.com
Pulmonary hypertension in interstitial lung disease: screeni... : Current Opinion in
Pulmonary Medicine Pulmonary hypertension in interstitial lung disease: screening …