Plasticity in the neonatal brain following hypoxic‐ischaemic injury

E Rocha-Ferreira, M Hristova - Neural plasticity, 2016 - Wiley Online Library
Hypoxic‐ischaemic damage to the developing brain is a leading cause of child death, with
high mortality and morbidity, including cerebral palsy, epilepsy, and cognitive disabilities …

The mechanisms and treatment of asphyxial encephalopathy

G Wassink, ER Gunn, PP Drury, L Bennet… - Frontiers in …, 2014 - frontiersin.org
Acute post-asphyxial encephalopathy occurring around the time of birth remains a major
cause of death and disability. The recent seminal insight that allows active neuroprotective …

Mitochondria: hub of injury responses in the developing brain

H Hagberg, C Mallard, CI Rousset… - The Lancet …, 2014 - thelancet.com
Progress in the field of mitochondrial biology in the past few years has shown that
mitochondrial activities go beyond bioenergetics. These new aspects of mitochondrial …

Redox-dependent loss of flavin by mitochondrial complex I in brain ischemia/reperfusion injury

A Stepanova, S Sosunov, Z Niatsetskaya… - Antioxidants & redox …, 2019 - liebertpub.com
Aims: Brain ischemia/reperfusion (I/R) is associated with impairment of mitochondrial
function. However, the mechanisms of mitochondrial failure are not fully understood. This …

PM2. 5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain

T Ku, X Ji, Y Zhang, G Li, N Sang - Chemosphere, 2016 - Elsevier
Air pollution is a serious environmental health problem that has been previously associated
with neuropathological disorders. However, current experimental evidence mainly focuses …

Hypoxic-ischemic encephalopathy and mitochondrial dysfunction: facts, unknowns, and challenges

M Rodríguez, V Valez, C Cimarra… - Antioxidants & redox …, 2020 - liebertpub.com
Significance: Hypoxic-ischemic events due to intrapartum complications represent the
second cause of neonatal mortality and initiate an acute brain disorder known as hypoxic …

Selective mitochondrial staining with small fluorescent probes: importance, design, synthesis, challenges and trends for new markers

BAD Neto, JR Corrêa, RG Silva - RSC advances, 2013 - pubs.rsc.org
The present manuscript describes the importance of small mitochondrion-specific
fluorescent markers to study mitochondrial dynamics and related processes. The importance …

Perinatal hypoxic-ischemic encephalopathy and neuroprotective peptide therapies: A case for cationic arginine-rich peptides (CARPs)

AB Edwards, RS Anderton, NW Knuckey, BP Meloni - Brain sciences, 2018 - mdpi.com
Perinatal hypoxic-ischemic encephalopathy (HIE) is the leading cause of mortality and
morbidity in neonates, with survivors suffering significant neurological sequelae including …

The effects of in utero fetal hypoxia and creatine treatment on mitochondrial function in the late gestation fetal sheep brain

AM Muccini, NT Tran, N Hale… - Oxidative Medicine …, 2022 - Wiley Online Library
Near‐term acute hypoxia in utero can result in significant fetal brain injury, with some brain
regions more vulnerable than others. As mitochondrial dysfunction is an underlying feature …

Влияние гипоксии на организм

СА Лобанов, ИВ Шишкин, НО Кузнецова… - … университета им. М …, 2017 - elibrary.ru
Анализ литературы позволил проследить особенности влияния гипоксии на организм и
формирование при этом ответных реакций. Показано, что значительные изменения …