Multilevel impacts of iron in the brain: the cross talk between neurophysiological mechanisms, cognition, and social behavior

A Ferreira, P Neves, R Gozzelino - Pharmaceuticals, 2019 - mdpi.com
Iron is a critical element for most organisms, which plays a fundamental role in the great
majority of physiological processes. So much so, that disruption of iron homeostasis has …

Deconstructing the functional neuroanatomy of the choroid plexus: an ontogenetic perspective for studying neurodevelopmental and neuropsychiatric disorders

BKY Bitanihirwe, P Lizano, TUW Woo - Molecular Psychiatry, 2022 - nature.com
The choroid plexus (CP) is a delicate and highly vascularized structure in the brain
comprised of a dense network of fenestrated capillary loops that help in the synthesis …

Characterization of age-related differences in the human choroid plexus volume, microstructural integrity, and blood perfusion using multiparameter magnetic …

JSR Alisch, M Kiely, C Triebswetter… - Frontiers in Aging …, 2021 - frontiersin.org
The choroid plexus (CP) is an important cerebral structure involved in cerebrospinal fluid
production and transport of solutes into the brain. Recent studies have uncovered the …

A preliminary choroid plexus volumetric study in individuals with psychosis

O Senay, M Seethaler, N Makris… - Human Brain …, 2023 - Wiley Online Library
The choroid plexus (ChP) is part of the blood‐cerebrospinal fluid barrier, regulating brain
homeostasis and the brain's response to peripheral events. Its upregulation and …

Non-invasive MRI of blood–cerebrospinal fluid barrier function

PG Evans, M Sokolska, A Alves, IF Harrison… - Nature …, 2020 - nature.com
The blood–cerebrospinal fluid barrier (BCSFB) is a highly dynamic transport interface that
serves brain homeostasis. To date, however, understanding of its role in brain development …

Preclinical characterization of macrophage-adhering gadolinium micropatches for MRI contrast after traumatic brain injury in pigs

LLW Wang, Y Gao, V Chandran Suja… - Science Translational …, 2024 - science.org
The choroid plexus (ChP) of the brain plays a central role in orchestrating the recruitment of
peripheral leukocytes into the central nervous system (CNS) through the blood …

Choroid plexus function in neurological homeostasis and disorders: The awakening of the circadian clocks and orexins

J Christensen, C Li… - Journal of Cerebral Blood …, 2022 - journals.sagepub.com
As research regarding the role of circadian rhythms, sleep, and the orexinergic system in
neurodegenerative diseases is growing, it is surprising that the choroid plexus (CP) remains …

Association of choroid plexus volume with serum biomarkers, clinical features, and disease severity in patients with frontotemporal lobar degeneration spectrum

M Assogna, E Premi, S Gazzina, A Benussi, NJ Ashton… - Neurology, 2023 - AAN Enterprises
Background and Objectives Choroid plexus (ChP) is emerging as a key brain structure in the
pathophysiology of neurodegenerative disorders. In this observational study, we …

Differences in the choroid plexus volume and microstructure are associated with body adiposity

JSR Alisch, JM Egan, M Bouhrara - Frontiers in Endocrinology, 2022 - frontiersin.org
The choroid plexus (CP) is a cerebral structure located in the ventricles that functions in
producing most of the brain's cerebrospinal fluid (CSF) and transporting proteins and …

Choroid plexuses at the interface of peripheral immunity and tissue repair in multiple sclerosis

VAG Ricigliano, B Stankoff - Current Opinion in Neurology, 2023 - journals.lww.com
ChP imaging metrics are emerging as possible biomarkers of neuroinflammation and repair
failure in MS. Future works combining multimodal imaging techniques should provide a …