Peptide-based vaccines: current progress and future challenges

RJ Malonis, JR Lai, O Vergnolle - Chemical reviews, 2019 - ACS Publications
Vaccines have had a profound impact on the management and prevention of infectious
disease. In addition, the development of vaccines against chronic diseases has attracted …

Next-generation influenza vaccines: opportunities and challenges

CJ Wei, MC Crank, J Shiver, BS Graham… - Nature reviews Drug …, 2020 - nature.com
Seasonal influenza vaccines lack efficacy against drifted or pandemic influenza strains.
Developing improved vaccines that elicit broader immunity remains a public health priority …

Advances in the development of influenza virus vaccines

F Krammer, P Palese - Nature reviews Drug discovery, 2015 - nature.com
Influenza virus infections are a major public health concern and cause significant morbidity
and mortality worldwide. Current influenza virus vaccines are an effective countermeasure …

[HTML][HTML] Current and next generation influenza vaccines: Formulation and production strategies

PC Soema, R Kompier, JP Amorij… - European Journal of …, 2015 - Elsevier
Vaccination is the most effective method to prevent influenza infection. However, current
influenza vaccines have several limitations. Relatively long production times, limited vaccine …

Towards a universal influenza vaccine: different approaches for one goal

GA Sautto, GA Kirchenbaum, TM Ross - Virology journal, 2018 - Springer
Influenza virus infection is an ongoing health and economic burden causing epidemics with
pandemic potential, affecting 5–30% of the global population annually, and is responsible …

[HTML][HTML] Universal influenza virus vaccines and therapeutic antibodies

R Nachbagauer, F Krammer - Clinical Microbiology and Infection, 2017 - Elsevier
Background Current influenza virus vaccines are effective when well matched to the
circulating strains. Unfortunately, antigenic drift and the high diversity of potential emerging …

Better influenza vaccines: an industry perspective

JR Chen, YM Liu, YC Tseng, C Ma - Journal of Biomedical Science, 2020 - Springer
Vaccination is the most effective measure at preventing influenza virus infections. However,
current seasonal influenza vaccines are only protective against closely matched circulating …

Universal vaccines and vaccine platforms to protect against influenza viruses in humans and agriculture

DS Rajão, DR Pérez - Frontiers in microbiology, 2018 - frontiersin.org
Influenza virus infections pose a significant threat to public health due to annual seasonal
epidemics and occasional pandemics. Influenza is also associated with significant economic …

Peptides for vaccine development

IW Hamley - ACS Applied Bio Materials, 2022 - ACS Publications
This review discusses peptide epitopes used as antigens in the development of vaccines in
clinical trials as well as future vaccine candidates. It covers peptides used in potential …

Universal influenza vaccines: Shifting to better vaccines

FB Scorza, V Tsvetnitsky, JJ Donnelly - Vaccine, 2016 - Elsevier
Influenza virus causes acute upper and lower respiratory infections and is the most likely,
among known pathogens, to cause a large epidemic in humans. Influenza virus mutates …