B-cell and antibody responses to SARS-CoV-2: infection, vaccination, and hybrid immunity

D Lapuente, TH Winkler, M Tenbusch - Cellular & Molecular …, 2024 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

JE Bowen, A Addetia, HV Dang, C Stewart, JT Brown… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

HLA variation and SARS-CoV-2 specific antibody response

D Wolday, CYJ Fung, G Morgan, S Casalino… - Viruses, 2023 - mdpi.com
Differences in SARS-CoV-2-specific immune responses have been observed between
individuals following natural infection or vaccination. In addition to already known factors …

Low levels of neutralizing antibodies against XBB Omicron subvariants after BA. 5 infection

J Yang, W Hong, H Lei, C He, W Lei, Y Zhou… - … and Targeted Therapy, 2023 - nature.com
The COVID-19 response strategies in Chinese mainland were recently adjusted due to the
reduced pathogenicity and enhanced infectivity of Omicron subvariants. In Chengdu, China …

Bivalent COVID-19 mRNA booster vaccination (BA. 1 or BA. 4/BA. 5) increases neutralization of matched Omicron variants

DN Springer, M Bauer, I Medits, JV Camp, SW Aberle… - npj Vaccines, 2023 - nature.com
We report SARS-CoV-2 neutralizing antibody titers in sera of triple-vaccinated individuals
who received a booster dose of an original monovalent or a bivalent BA. 1-or BA. 4/BA. 5 …

Different neutralization profiles after primary SARS-CoV-2 Omicron BA. 1 and BA. 2 infections

I Medits, DN Springer, M Graninger, JV Camp… - Frontiers in …, 2022 - frontiersin.org
Background and Methods The SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2) Omicron (B. 1.1. 529) variant is the antigenically most distinct variant to date …

Reduced sensitivity of commercial spike-specific antibody assays after primary infection with the SARS-CoV-2 Omicron variant

DN Springer, T Perkmann, CM Jani… - Microbiology …, 2022 - Am Soc Microbiol
ABSTRACT The SARS-CoV-2 Omicron variant is characterized by substantial changes in
the antigenic structure of the Spike (S) protein. Therefore, antibodies induced by primary …

An overview of viral mutagenesis and the impact on pathogenesis of SARS-CoV-2 variants

MZI Khan, A Nazli, H Al-Furas, MI Asad, I Ajmal… - Frontiers in …, 2022 - frontiersin.org
Viruses are submicroscopic, obligate intracellular parasites that carry either DNA or RNA as
their genome, protected by a capsid. Viruses are genetic entities that propagate by using the …

Immune interference in effectiveness of influenza and COVID-19 vaccination

Y Xie, X Tian, X Zhang, H Yao, N Wu - Frontiers in immunology, 2023 - frontiersin.org
Vaccines are known to function as the most effective interventional therapeutics for
controlling infectious diseases, including polio, smallpox, rabies, tuberculosis, influenza and …

Immunological imprinting of humoral immunity to SARS-CoV-2 in children

AC Dowell, T Lancaster, R Bruton, G Ireland… - Nature …, 2023 - nature.com
Omicron variants of SARS-CoV-2 are globally dominant and infection rates are very high in
children. We measure immune responses following Omicron BA. 1/2 infection in children …