Biologics—medications derived from a biological source—are increasingly used as
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …

Biopolymeric nanoparticulate systems hold favorable carrier properties for active delivery.
The enhancement in the research interest in alginate formulations in biomedical and …

Over the recent decades the interest in intranasal delivery as a non-invasive route for drugs
is increased. Since the nasal mucosa offers numerous benefits as a target tissue for drug …

Most existing vaccines for human use are administered by needle-based injection.
Administering vaccines needle-free intranasally has numerous advantages over by needle …

Introduction: Many therapeutics are limited to parenteral administration. Oral administration
is a desirable alternative because of the convenience and increased compliance by …

Biodegradable core− shell structured nanoparticles with a poly (β-amino ester)(PBAE) core
enveloped by a phospholipid bilayer shell were developed for in vivo mRNA delivery with a …

Because of their large surface area and immunological competence, mucosal tissues are
attractive administration and target sites for vaccination. An important characteristic of …

Background An association was previously established between facial nerve paralysis
(Bell's palsy) and intranasal administration of an inactivated influenza virosome vaccine …

Intranasal administration is an attractive option for local and systemic delivery of many
therapeutic agents. The nasal mucosa is–compared to other mucosae–easily accessible …

Vaccine delivery via mucosal surfaces is an interesting alternative to parenteral vaccine
administration, as it avoids the use of a needle and syringe. Mucosal vaccine administration …