Exosome-based vaccines: history, current state, and clinical trials
P Santos, F Almeida - Frontiers in immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by most cell types as part of an intracellular
communication system in crucial processes such as inflammation, cell proliferation, and …
communication system in crucial processes such as inflammation, cell proliferation, and …
Tumor-derived extracellular vesicles: The metastatic organotropism drivers
The continuous growing, spreading, and metastasis of tumor cells depend on intercellular
communication within cells resident in a tissue environment. Such communication is …
communication within cells resident in a tissue environment. Such communication is …
Universal immunotherapeutic strategy for hepatocellular carcinoma with exosome vaccines that engage adaptive and innate immune responses
B Zuo, Y Zhang, K Zhao, L Wu, H Qi, R Yang… - Journal of hematology & …, 2022 - Springer
Background Personalized immunotherapy utilizing cancer vaccines tailored to the tumors of
individual patients holds promise for tumors with high genetic heterogeneity, potentially …
individual patients holds promise for tumors with high genetic heterogeneity, potentially …
[HTML][HTML] Extracellular vesicles: emerging tools as therapeutic agent carriers
Extracellular vesicles (EVs) are secreted by both eukaryotes and prokaryotes, and are
present in all biological fluids of vertebrates, where they transfer DNA, RNA, proteins, lipids …
present in all biological fluids of vertebrates, where they transfer DNA, RNA, proteins, lipids …
[HTML][HTML] Small extracellular vesicles in cancer
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
Biosynthetic dendritic cell-exocytosed aggregation-induced emission nanoparticles for synergistic photodynamic immunotherapy
H Cao, H Gao, L Wang, Y Cheng, X Wu, X Shen… - ACS …, 2022 - ACS Publications
Dendritic cell (DC)-derived small extracellular vesicles (DEVs) are recognized as a highly
promising alternative to DC vaccines; however, the clinical testing of DEV-based …
promising alternative to DC vaccines; however, the clinical testing of DEV-based …
Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities
A Vahabi, J Rezaie, M Hassanpour, Y Panahi… - Biochemical …, 2022 - Elsevier
Recently, circular RNAs (circRNAs) have appealed to a growing interest due to their
abundant expression and potential functions in cancer development. The most biological …
abundant expression and potential functions in cancer development. The most biological …
Emerging role of cancer-associated fibroblasts-derived exosomes in tumorigenesis
L Peng, D Wang, Y Han, T Huang, X He… - Frontiers in …, 2022 - frontiersin.org
Cancer-associated fibroblasts (CAFs) are the most important component of the stromal cell
population in the tumor microenvironment and play an irreplaceable role in oncogenesis …
population in the tumor microenvironment and play an irreplaceable role in oncogenesis …
Protein corona and exosomes: new challenges and prospects
Recent advances in extracellular vesicle (EVs) detection and isolation methods have led to
the development of novel therapeutic modalities. Among different types of EVs, exosomes …
the development of novel therapeutic modalities. Among different types of EVs, exosomes …
[HTML][HTML] Recent progress of dendritic cell-derived exosomes (Dex) as an anti-cancer nanovaccine
J Xia, Y Miao, X Wang, X Huang, J Dai - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Although cancer vaccines such as dendritic cell (DC) vaccines and peptide vaccines have
become appealing and attractive anticancer immunotherapy options in recent decades …
become appealing and attractive anticancer immunotherapy options in recent decades …