Intra-organ delivery of nanotherapeutics for organ transplantation

B Hussain, V Kasinath, JC Madsen, J Bromberg… - ACS …, 2021 - ACS Publications
Targeted delivery of therapeutics through the use of nanoparticles (NPs) has emerged as a
promising method that increases their efficacy and reduces their side effects. NPs can be …

Hybrid lymphatic drug delivery vehicles as a new avenue for targeted therapy: Lymphatic trafficking, applications, challenges, and future horizons

GI Harisa, AY Sherif, FK Alanazi - The Journal of Membrane Biology, 2023 - Springer
Lymphatic drug targeting is an effective approach for targeting immunomodulators, and
chemotherapeutic drugs at a specific organ or cellular location. The cellular, paracellular …

A lymphatic-absorbed multi-targeted kinase inhibitor for myelofibrosis therapy

BD Ross, Y Jang, A Welton, CA Bonham… - Nature …, 2022 - nature.com
Activation of compensatory signaling nodes in cancer often requires combination therapies
that are frequently plagued by dose-limiting toxicities. Intestinal lymphatic drug absorption is …

Unlocking the power of sugar: carbohydrate ligands as key players in nanotherapeutic-assisted targeted cancer therapy

R Swami, S Vij, S Sharma - Nanomedicine, 2024 - Taylor & Francis
Cancer cells need as much as 40-times more sugar than their normal cell counterparts. This
sugar demand is attained by the excessive expression of inimitable transporters on the …

Nanotechnology-Enhanced Naloxone and Alternative Treatments for Opioid Addiction

IM Heyns, AF Faunce, MN Mumba… - ACS Pharmacology & …, 2024 - ACS Publications
Opioids are commonly prescribed to address intense, ongoing pain associated with cancer,
as well as long-lasting noncancer-related pain when alternative methods have proven …

State-of-the-art drug delivery system to target the lymphatics

OT Khaire, A Mhaske, AG Prasad… - Journal of Drug …, 2024 - Taylor & Francis
Abstract Primary Objective The primary objective of the review is to assess the potential of
lymphatic-targeted drug delivery systems, with a particular emphasis on their role in tumour …

Self-micro emulsifying drug delivery via intestinal lymphatics: a lucrative approach to drug targeting

DP Ramachandra, P Sudheer - Pharmaceutical …, 2023 - ingentaconnect.com
The intestinal lymphatics are considered one of the most specialized pathways, which
promote the absorption of various agents such as vitamins, lipids, xenobiotics, and lipophilic …

Stannous colloid mixed with indocyanine green as a tracer for sentinel lymph node navigation surgery

Y Zhang, T Uehara, T Toyota, R Endo, H Matsubara… - Scientific Reports, 2022 - nature.com
The combined use of a vital dye and radioactive colloid reportedly performs better in
detecting sentinel lymph nodes (SLNs) for cancers than the use of either of them alone …

Physicochemical Properties of Carriers for Targeting Lymphatic System

CE Umeyor, P Kumbhar, R Trivedi, P Kolekar… - Advanced Targeting of …, 2024 - Springer
The lymphatic biology plays pivotal roles in human health due to overwhelming impacts of
the lymphatic processes, mechanisms, regulations, and functions. It is, therefore, evidently …

Transdermal Application of Nanoparticles for Targeting Lymphatic System

D Kulkarni, P Panzade, V Bodhankar… - Advanced Targeting of …, 2024 - Springer
Transdermal route of administration provides a versatile and efficient approach for the
delivery of various drug categories. Transdermal drug delivery through nanocarriers …