Pregnancy is a dynamic and precisely organized process during which one or more baby
develops. Embryonic development relies on the formation of the placenta, allowing nutrient …

Chronic kidney disease (CKD) affects~ 10% of the population and cardiovascular disease is
its commonest complication. Despite treatment, patient outcomes remain poor and newer …

Background Polycystic ovary syndrome (PCOS) is one of the most common gynecological
endocrine disorders. Apelin and chemerin are newly identified adipokines, which are higher …

Purpose Diabetic heart failure (DHF) or cardiomyopathy is a common complication of
diabetes; however, the underlying mechanism is not clear. In the present study, the authors …

Type 2 diabetes mellitus (T2DM) remains a powerful predictor of progressive heart failure
(HF), but it is not clear whether altered glycemic control interferes with HF progression via an …

Apelin is a bioactive peptide and the endogenous ligand of APJ, a G-protein–coupled
receptor. It is expressed in several organs and tissues including many regions of the central …

Background and Aims. Exercise activity is an important method for managing type 2
diabetes. This investigation examined the HIIT and continuous training on apelin, APJ …

Aims: This systematic review and meta-analysis investigated maternal apelin levels in
pregnant women with and without GDM. Secondary outcomes were glucose-and lipid …

The apelin receptor (Aplnr) and its ligands, Apelin and Apela, contribute to metabolic control.
The insulin resistance associated with pregnancy is accommodated by an expansion of …

The increasing morbidity and mortality of type 2 diabetic mellitus (T2DM) patients with
ischemic heart disease (IHD) highlight an urgent need to identify early biomarkers, which …