Compromised SARS-CoV-2-specific placental antibody transfer

C Atyeo, KM Pullen, EA Bordt, S Fischinger, J Burke… - Cell, 2021 - cell.com
SARS-CoV-2 infection causes more severe disease in pregnant women compared to age-
matched non-pregnant women. Whether maternal infection causes changes in the transfer …

Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses

EA Bordt, LL Shook, C Atyeo, KM Pullen… - Science translational …, 2021 - science.org
There is a persistent bias toward higher prevalence and increased severity of coronavirus
disease 2019 (COVID-19) in males. Underlying mechanisms accounting for this sex …

A longitudinal SARS-CoV-2 biorepository for COVID-19 survivors with and without post-acute sequelae

SM LaVergne, S Stromberg, BA Baxter, TL Webb… - BMC infectious …, 2021 - Springer
Background SARS-CoV-2 has swept across the globe, causing millions of deaths
worldwide. Though most survive, many experience symptoms of COVID-19 for months after …

Accelerated longitudinal weight gain among infants with in utero COVID-19 exposure

MW Ockene, SC Russo, H Lee… - The Journal of …, 2023 - academic.oup.com
Context Since the initial outbreak of coronavirus disease 2019 (COVID-19), a novel
population of children with in utero exposure to maternal infection has emerged whose …

COVID-19 and pregnancy: a comparison of case reports, case series and registry studies

EM Young, O Green, J Stewart, Y King… - European Journal of …, 2022 - Elsevier
Background Selection, outcome and publication biases are well described in case reports
and case series but may be less of a problem early in the appearance of a new disease …

Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation

JD Matute, B Finander, D Pepin, X Ai, NP Smith… - Pediatric …, 2022 - nature.com
Background During the COVID-19 pandemic, thousands of pregnant women have been
infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The …

Pandemic response requires research samples: a US safety-net hospital's experience and call for national action

EJ Ragan, C McCallum, J Marathe, M Cole… - Annals of internal …, 2021 - acpjournals.org
Biorepositories provide a critical resource for gaining knowledge of emerging infectious
diseases and offer a mechanism to rapidly respond to outbreaks; the emergence of the …

Placental expression of ACE2 and TMPRSS2 in maternal severe acute respiratory syndrome coronavirus 2 infection: are placental defenses mediated by fetal sex?

LL Shook, EA Bordt, MC Meinsohn… - The Journal of …, 2021 - academic.oup.com
Background Expression of angiotensin-converting enzyme 2 (ACE2) and type II
transmembrane serine protease (TMPRSS2), host molecules required for viral entry, may …

SARS-CoV-2 infection elucidates features of pregnancy-specific immunity

DS Oh, E Kim, R Normand, G Lu, LL Shook, A Lyall… - Cell Reports, 2024 - cell.com
Pregnancy is a risk factor for increased severity of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and other respiratory infections, but the mechanisms …

Sexually dimorphic placental responses to maternal SARS-CoV-2 infection

EA Bordt, LL Shook, C Atyeo, KM Pullen… - bioRxiv, 2021 - biorxiv.org
There is a persistent male bias in the prevalence and severity of COVID-19 disease.
Underlying mechanisms accounting for this sex difference remain incompletely understood …