Relationship between agrochemical compounds and mammary gland development and breast cancer

L Kass, AL Gomez, GA Altamirano - Molecular and cellular endocrinology, 2020 - Elsevier
The exposure to agrochemical pesticides has been associated with several chronic
diseases, including different types of cancer and reproductive disorders. In addition …

Best practices to quantify the impact of reproductive toxicants on development, function, and diseases of the rodent mammary gland

K Matouskova, GK Szabo, J Daum, SE Fenton… - Reproductive …, 2022 - Elsevier
Work from numerous fields of study suggests that exposures to hormonally active chemicals
during sensitive windows of development can alter mammary gland development, function …

[HTML][HTML] Estrogens and endocrine-disrupting chemicals differentially impact the bioenergetic fluxes of mammary epithelial cells in two-and three-dimensional models

A Lacouture, Y Breton, C Weidmann, SM Goulet… - Environment …, 2023 - Elsevier
Due to its sensitivity to hormonal signaling, the mammary gland is often referred to as a
sentinel organ for the study of endocrine-disrupting chemicals (EDCs), environmental …

Exposure to low doses of oxybenzone during perinatal development alters mammary gland morphology in male and female mice

K Matouskova, DJ Jerry, LN Vandenberg - Reproductive Toxicology, 2020 - Elsevier
Abstract Oxybenzone (benzophenone-3) is an ultraviolet radiation filter commonly used in
personal care products including sunscreens, textiles and inks, and food and beverage …

Postnatal exposure to a glyphosate-based herbicide modifies mammary gland growth and development in Wistar male rats

GA Altamirano, MB Delconte, AL Gomez… - Food and chemical …, 2018 - Elsevier
Our aim was to evaluate whether postnatal exposure to a glyphosate-based herbicide (GBH)
modifies mammary gland development in pre-and post-pubertal male rats. From postnatal …

REPRODUCTIVE TOXICOLOGY: the male mammary gland: a novel target of endocrine-disrupting chemicals

GK Szabo, LN Vandenberg - Reproduction, 2021 - rep.bioscientifica.com
In the past several decades, the incidence of two male breast diseases, gynecomastia and
male breast cancer, have increased in human populations. Whereas male breast cancer …

Mouse mammary gland whole mount preparation and analysis

C Tolg, M Cowman, EA Turley - Bio-protocol, 2018 - bio-protocol.org
The mammary gland undergoes extensive remodeling during pregnancy and is also subject
to neoplastic processes both of which result in histological changes of the gland epithelial …

Endocrine disrupting chemicals and the mammary gland

LN Vandenberg - Advances in Pharmacology, 2021 - Elsevier
Abstract Development of the mammary gland requires coordination of hormone signaling
pathways including those mediated by estrogen, progesterone, androgen and prolactin …

Bisphenol S alters development of the male mouse mammary gland and sensitizes it to a peripubertal estrogen challenge

SDD Kolla, DB McSweeney, A Pokharel… - Toxicology, 2019 - Elsevier
Humans are exposed to estrogenic chemicals in food and food packaging, personal care
products, and other industrial and consumer goods. Bisphenol A (BPA), a well-studied …

The tributyltin leads to obesogenic mammary gland abnormalities in adult female rats

CS da Costa, L Miranda-Alves, MA La Merrill, IV Silva… - Toxicology Letters, 2019 - Elsevier
Tributyltin chloride (TBT) is an obesogen associated with several complications. However,
few investigations have evaluated TBT effects on adult mammary glands (MG). In this …