IL-10 and IL-22 in mucosal immunity: driving protection and pathology
HX Wei, B Wang, B Li - Frontiers in Immunology, 2020 - frontiersin.org
The barrier surfaces of the gastrointestinal tract are in constant contact with various
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …
Interleukin-22: immunobiology and pathology
JA Dudakov, AM Hanash… - Annual review of …, 2015 - annualreviews.org
Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T
helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs) …
helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs) …
T helper cells: the modulators of inflammation in multiple sclerosis
M Kunkl, S Frascolla, C Amormino, E Volpe, L Tuosto - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors
In vertebrates, including humans, individuals harbor gut microbial communities whose
species composition and relative proportions of dominant microbial groups are …
species composition and relative proportions of dominant microbial groups are …
Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases
M Akdis, S Burgler, R Crameri, T Eiwegger… - Journal of allergy and …, 2011 - Elsevier
Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …
autoimmune diseases, tumor development, organ transplantation, and chronic infections …
Regulation of interferon‐γ during innate and adaptive immune responses
JR Schoenborn, CB Wilson - Advances in immunology, 2007 - Elsevier
Abstract Interferon‐γ (IFN‐γ) is crucial for immunity against intracellular pathogens and for
tumor control. However, aberrant IFN‐γ expression has been associated with a number of …
tumor control. However, aberrant IFN‐γ expression has been associated with a number of …
Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway
NC Sondermann, S Faßbender, F Hartung… - Biochemical …, 2023 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating
adaptive and maladaptive responses toward exogenous and endogenous signals …
adaptive and maladaptive responses toward exogenous and endogenous signals …
IL-22 increases the innate immunity of tissues
K Wolk, S Kunz, E Witte, M Friedrich, K Asadullah… - Immunity, 2004 - cell.com
Abstract Interleukin 22 (IL-22) is mainly produced by activated Th1 cells. The data presented
here indicate that neither resting nor activated immune cells express IL-22 receptor, and IL …
here indicate that neither resting nor activated immune cells express IL-22 receptor, and IL …
Interleukin-10 therapy—review of a new approach
K Asadullah, W Sterry, HD Volk - Pharmacological reviews, 2003 - ASPET
Interleukin (IL)-10 is an important immunoregulatory cytokine produced by many cell
populations. Its main biological function seems to be the limitation and termination of …
populations. Its main biological function seems to be the limitation and termination of …