[HTML][HTML] Pulsed electromagnetic fields in bone healing: molecular pathways and clinical applications

L Caliogna, M Medetti, V Bina, AM Brancato… - International Journal of …, 2021 - mdpi.com
In this article, we provide an extensive review of the recent literature of the signaling
pathways modulated by Pulsed Electromagnetic Fields (PEMFs) and PEMFs clinical …

Underlying signaling pathways and therapeutic applications of pulsed electromagnetic fields in bone repair

J Yuan, F Xin, W Jiang - Cellular Physiology and Biochemistry, 2018 - karger.com
Pulsed electromagnetic field (PEMF) stimulation, as a prospective, noninvasive, and safe
physical therapy strategy to accelerate bone repair has received tremendous attention in …

[HTML][HTML] Targeting mesenchymal stromal cells/pericytes (MSCs) with pulsed electromagnetic field (PEMF) has the potential to treat rheumatoid arthritis

CL Ross, DC Ang, G Almeida-Porada - Frontiers in immunology, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic
inflammation of synovium (synovitis), with inflammatory/immune cells and resident fibroblast …

The use of electric, magnetic, and electromagnetic field for directed cell migration and adhesion in regenerative medicine

CL Ross - Biotechnology progress, 2017 - Wiley Online Library
Directed cell migration and adhesion is essential to embryonic development, tissue
formation and wound healing. For decades it has been reported that electric field (EF) …

[HTML][HTML] Primary human osteoblasts with reduced alkaline phosphatase and matrix mineralization baseline capacity are responsive to extremely low frequency pulsed …

S Ehnert, K Falldorf, AK Fentz, P Ziegler, S Schröter… - Bone Reports, 2015 - Elsevier
For many years electromagnetic fields (EMFs) have been used clinically with various
settings as an exogenous stimulation method to promote fracture healing. However …

Effects and mechanisms of exogenous electromagnetic field on bone cells: a review

B Zhang, Y Xie, Z Ni, L Chen - Bioelectromagnetics, 2020 - Wiley Online Library
Osteoporosis, fractures, and other bone diseases or injuries represent serious health
problems in modern society. A variety of treatments including drugs, surgeries, physical …

Coupling induction of osteogenesis and type H vessels by pulsed electromagnetic fields in ovariectomy-induced osteoporosis in mice

Q Wang, J Zhou, X Wang, Y Xu, Z Liang, X Gu, C He - Bone, 2022 - Elsevier
The growth of blood vessels and osteogenesis are coupled in bone tissue. A specialized
subset of CD31 hi Endomucin hi (CD31 hi Emcn hi) vascular endothelium in bone has been …

[HTML][HTML] Towards an effective sensing technology to monitor micro-scale interface loosening of bioelectronic implants

MP Soares dos Santos, R Bernardo, L Henriques… - Scientific Reports, 2021 - nature.com
Instrumented implants are being developed with a radically innovative design to significantly
reduce revision surgeries. Although bone replacements are among the most prevalent …

Pulsed electromagnetic fields promote bone formation by activating the sAC–cAMP–PKA–CREB signaling pathway

YY Wang, XY Pu, WG Shi, QQ Fang… - Journal of Cellular …, 2019 - Wiley Online Library
The application of pulsed electromagnetic fields (PEMFs) in the prevention and treatment of
osteoporosis has long been an area of interest. However, the clinical application of PEMFs …

[HTML][HTML] Co-culture with human osteoblasts and exposure to extremely low frequency pulsed electromagnetic fields improve osteogenic differentiation of human …

S Ehnert, M Van Griensven, M Unger… - International journal of …, 2018 - mdpi.com
Human adipose-derived mesenchymal stem cells (Ad-MSCs) have been proposed as
suitable option for cell-based therapies to support bone regeneration. In the bone …