Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments

N Tandon, SS Yadav - Journal of Ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Withania somnifera popularly known as Aswagandha or
Indian Ginseng/Poison Gooseberry have thousands years of history of use in Indian …

[HTML][HTML] Exploring the multifaceted therapeutic potential of withaferin A and its derivatives

T Behl, A Sharma, L Sharma, A Sehgal, G Zengin… - Biomedicines, 2020 - mdpi.com
Withaferin A (WA), a manifold studied, C28-steroidal lactone withanolide found in Withania
somnifera. Given its unique beneficial effects, it has gathered attention in the era of modern …

[HTML][HTML] Hairy root culture: a potent method for improved secondary metabolite production of Solanaceous plants

D Biswas, A Chakraborty, S Mukherjee… - Frontiers in Plant …, 2023 - frontiersin.org
Secondary metabolites synthesized by the Solanaceous plants are of major therapeutic and
pharmaceutical importance, many of which are commonly obtained from the roots of these …

[HTML][HTML] Withaferin A: from ancient remedy to potential drug candidate

T Sultana, MK Okla, M Ahmed, N Akhtar, A Al-Hashimi… - Molecules, 2021 - mdpi.com
Withaferin A (WA) is a pivotal withanolide that has conquered a conspicuous place in
research, owning to its multidimensional biological properties. It is an abundant constituent …

Chemistry and pharmacology of Withania somnifera: An update

V Kumar, A Dey, MB Hadimani, T Marcovic, M Emerald - CellMed, 2015 - koreascience.kr
Withania somnifera (Ashwagandha) is an important Rasayana herb and widely considered
as Indian ginseng in Ayurveda. In traditional system of Indian medicine, it is used as tonic to …

[HTML][HTML] Structure model index does not measure rods and plates in trabecular bone

PL Salmon, C Ohlsson, SJ Shefelbine… - Frontiers in …, 2015 - frontiersin.org
Structure model index (SMI) is widely used to measure rods and plates in trabecular bone. It
exploits the change in surface curvature that occurs as a structure varies from spherical …

[HTML][HTML] An updated review on phytochemistry and molecular targets of Withania somnifera (L.) Dunal (Ashwagandha)

A Bashir, M Nabi, N Tabassum, S Afzal… - Frontiers in …, 2023 - frontiersin.org
Withania somnifera (L.) Dunal belongs to the nightshade family Solanaceae and is
commonly known as Ashwagandha. It is pharmacologically a significant medicinal plant of …

[HTML][HTML] Electrically polarized withaferin a and alginate-incorporated biphasic calcium phosphate microspheres exhibit osteogenicity and antibacterial activity in vitro

I Priyadarshini, S Swain, JR Koduru, TR Rautray - Molecules, 2022 - mdpi.com
Biphasic calcium phosphate microspheres were synthesized by the water on oil emulsion
method and, subsequently, withaferin A was incorporated in the microspheres to evaluate …

Dietary nutraceuticals as backbone for bone health

MK Pandey, SC Gupta, D Karelia, PJ Gilhooley… - Biotechnology …, 2018 - Elsevier
Bone loss or osteoporosis, is a slow-progressing disease that results from dysregulation of
pro-inflammatory cytokines. The FDA has approved number of drugs for bone loss …

Co‐expression of Arabidopsis transcription factor, AtMYB12, and soybean isoflavone synthase, GmIFS1, genes in tobacco leads to enhanced biosynthesis of …

A Pandey, P Misra, MP Khan… - Plant biotechnology …, 2014 - Wiley Online Library
Isoflavones, a group of flavonoids, restricted almost exclusively to family Leguminosae are
known to exhibit anticancerous and anti‐osteoporotic activities in animal systems and have …