Aging is associated with a progressive decline of brain function, and the underlying causes
and possible interventions to prevent this cognitive decline have been the focus of intense …

Mutations in the X-linked methyl-CpG-binding protein 2 (MECP2) gene cause Rett
syndrome, a severe childhood neurological disorder. MeCP2 is a well-established …

Astrocytes provide crucial support for neurons, contributing to synaptogenesis, synaptic
maintenance, and neurotransmitter recycling. Under pathological conditions, deregulation of …

With the aging of the global population, neurodegenerative diseases are emerging as a
major public health issue. The adoption of a less sedentary lifestyle has been shown to have …

Changes in the epigenetic landscape are a hallmark of aging that contributes to the
irreversible decline in organismal fitness ultimately leading to aging-related diseases …

Physical exercise represents a primary defense against age-related cognitive decline and
neurodegenerative disorders like Alzheimer's disease (AD). To impartially investigate the …

Frontotemporal dementia is a debilitating neurodegenerative disorder characterized by
frontal and temporal lobe degeneration, resulting in behavioral changes, language …

As the global population ages, the prevalence of neurodegenerative diseases has become
a major public health concern. The adoption of a less sedentary lifestyle has been shown to …