Recent advances in exosome-mediated nucleic acid delivery for cancer therapy

Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …

The ambiguous role of sirtuins in head and neck squamous cell carcinoma

D Ezhilarasan, T Lakshmi, M Subha… - Oral …, 2022 - Wiley Online Library
Oral cancer is one of the most leading cancer responsible for significant morbidity and
mortality. The sirtuins (SIRTs) are a family of class III histone deacetylases and are known to …

Cancer drug resistance induced by EMT: novel therapeutic strategies

J De Las Rivas, A Brozovic, S Izraely, A Casas-Pais… - Archives of …, 2021 - Springer
Over the last decade, important clinical benefits have been achieved in cancer patients by
using drug-targeting strategies. Nevertheless, drug resistance is still a major problem in …

Drug delivery (nano) platforms for oral and dental applications: tissue regeneration, infection control, and cancer management

P Makvandi, U Josic, M Delfi, F Pinelli… - Advanced …, 2021 - Wiley Online Library
The oral cavity and oropharynx are complex environments that are susceptible to physical,
chemical, and microbiological insults. They are also common sites for pathological and …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Extracellular vesicles in cancer drug resistance: roles, mechanisms, and implications

Q Yang, J Xu, J Gu, H Shi, J Zhang, J Zhang… - Advanced …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐derived nanosized vesicles that mediate cell‐to‐cell
communication via transporting bioactive molecules and thus are critically involved in …

Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer

KA Preethi, SC Selvakumar, K Ross, S Jayaraman… - Molecular Cancer, 2022 - Springer
Background Detecting cancer at an early stage before clinical manifestation could be an
effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy biomarkers …

Mesenchymal stem cell-derived exosomes loaded with miR-155 inhibitor ameliorate diabetic wound healing

P Gondaliya, AA Sayyed, P Bhat, M Mali… - Molecular …, 2022 - ACS Publications
Diabetic wounds are one of the debilitating complications that affect up to 20% of diabetic
patients. Despite the advent of extensive therapies, the recovery rate is unsatisfactory, and …

Trends in research on exosomes in cancer progression and anticancer therapy

D Sinha, S Roy, P Saha, N Chatterjee, A Bishayee - Cancers, 2021 - mdpi.com
Simple Summary Intensive research in the field of cancer biology has discovered a unique
mode of interplay between cells via extracellular bioactive vesicles called exosomes …

Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application

Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …