Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

Liver cancer has the fourth highest mortality rate of all cancers worldwide, with
hepatocellular carcinoma (HCC) being the most prevalent subtype. Despite great advances …

The human liver is usually perceived as a non-immunological organ engaged primarily in
metabolic, nutrient storage and detoxification activities. However, we now know that the …

The liver is a central immunological organ with a high exposure to circulating antigens and
endotoxins from the gut microbiota, particularly enriched for innate immune cells …

Receiving both portal vein blood and arterial blood, the liver is an important and critical
component in the defense against blood-borne infection. To accomplish this role, the liver …

This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

The liver is an immunologically tolerant organ that is uniquely equipped to limit
hypersensitivity to food-derived antigens and bacterial products through the portal vein and …

Dendritic cells (DC) are professional antigen presenting cells comprising a variety of
subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the …

The demands that are imposed on the liver as a result of its function as a metabolic organ
that extracts nutrients and clears gut-derived microbial products from the blood are met by a …

The hepatic immune system is constantly exposed to a massive load of harmless dietary and
commensal antigens, to which it must remain tolerant. Immune tolerance in the liver is …