Spinal cord injury (SCI) is a life-shattering neurological condition that affects between
250,000 and 500,000 individuals each year with an estimated two to three million people …

Traumatic spinal cord injury (SCI) has widespread physiological effects beyond the
disruption of sensory and motor function, notably the loss of normal autonomic and …

Spinal cord injury (SCI) damages multiple structures at the lesion site, including ascending,
descending, and propriospinal axons; interrupting the conduction of information up and …

Cervical spinal cord injury interrupts supraspinal pathways innervating thoracic sympathetic
preganglionic neurons and results in cardiovascular dysfunction. Both respiratory and …

Objectives: Identify clinical and pathophysiologic insights into autonomic dysreflexia (AD) in
patients with spinal cord injury (SCI). Study Design: Analysis of prospectively gathered AD …

High-level spinal cord injury commonly leads to blood pressure instability. This manifests
clinically as orthostatic hypotension (OH), where blood pressure can drop to the point of loss …

Baroreflex activation by electric stimulation of the carotid sinus (CS) effectively lowers blood
pressure. However, the degree to which differences between stimulation protocols impinge …

Autonomic dysreflexia (AD) is a life-threatening condition for individuals with cervical or high-
thoracic spinal cord injury (SCI). The profile of autonomic dysfunction in AD using validated …

The effects of spinal cord injury (SCI) on sympathetic neurovascular transmission have
generally been ignored. This review describes changes in sympathetic nerve-mediated …

Objectives Systemic left-to-right shunting causes pulmonary arteriopathy, leading to
progressive cardiopulmonary failure and a poor prognosis. In this study, we examined the …