The role of extracellular vesicles in cancer
R Kalluri, KM McAndrews - Cell, 2023 - cell.com
Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …
[HTML][HTML] Natural and synthetic nanovectors for cancer therapy
Nanomaterials have been extensively studied in cancer therapy as vectors that may improve
drug delivery. Such vectors not only bring numerous advantages such as stability …
drug delivery. Such vectors not only bring numerous advantages such as stability …
Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy
Neutrophils are the most abundant innate immune cells in human circulation; however, their
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
Prevalence and disease burden of chronic kidney disease
JC Lv, LX Zhang - Renal fibrosis: mechanisms and therapies, 2019 - Springer
Chronic kidney disease (CKD) has been recognized as a leading public health problem
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
[HTML][HTML] Exosome engineering: Current progress in cargo loading and targeted delivery
Exosomes, a class of small bilayer vesicles derived from virtually all eukaryotic cells, have
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment
Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
Tumor-derived exosomes (TDEs) participate in formation and progression of different cancer
processes, including tumor microenvironment (TME) remodeling, angiogenesis, invasion …
processes, including tumor microenvironment (TME) remodeling, angiogenesis, invasion …
Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
T Yong, X Zhang, N Bie, H Zhang, X Zhang, F Li… - Nature …, 2019 - nature.com
Developing biomimetic nanoparticles without loss of the integrity of proteins remains a major
challenge in cancer chemotherapy. Here, we develop a biocompatible tumor-cell …
challenge in cancer chemotherapy. Here, we develop a biocompatible tumor-cell …
Extracellular vesicles in cancer—implications for future improvements in cancer care
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …
cell–cell communication within complex tissue environments. Such communication …
Challenges in the development and establishment of exosome-based drug delivery systems
J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …