Nanoparticle characterization: state of the art, challenges, and emerging technologies

EJ Cho, H Holback, KC Liu… - Molecular …, 2013 - ACS Publications
Nanoparticles have received enormous attention as a promising tool to enhance target-
specific drug delivery and diagnosis. Various in vitro and in vivo techniques are used to …

Noncovalent interaction-assisted polymeric micelles for controlled drug delivery

J Ding, L Chen, C Xiao, L Chen, X Zhuang… - Chemical …, 2014 - pubs.rsc.org
Polymeric micelles are one of the most promising nanovehicles for drug delivery. In addition
to amphiphilicity, various individual or synergistic noncovalent interplays including strong …

Ni-Catalyzed Carboxylation of Unactivated Primary Alkyl Bromides and Sulfonates with CO2

Y Liu, J Cornella, R Martin - Journal of the American Chemical …, 2014 - ACS Publications
A Ni-catalyzed carboxylation of unactivated primary alkyl bromides and sulfonates with CO2
at atmospheric pressure is described. The method is characterized by its mild conditions and …

Highly augmented drug loading and stability of micellar nanocomplexes composed of doxorubicin and poly (ethylene glycol)–green tea catechin conjugate for cancer …

K Liang, JE Chung, SJ Gao… - Advanced …, 2018 - Wiley Online Library
Low drug loading and instability in blood circulation are two key challenges that impede the
successful clinical translation of nanomedicine, as they result in only marginal therapeutic …

Amphiphilic poly (amino acid) based micelles applied to drug delivery: The in vitro and in vivo challenges and the corresponding potential strategies

H Xu, Q Yao, C Cai, J Gou, Y Zhang, H Zhong… - Journal of Controlled …, 2015 - Elsevier
Core–shell structured micelles produced from an amphiphilic block copolymer are promising
drug delivery vehicles because their hydrophobic core can encapsulate hydrophobic drugs …

Noncovalent polymer‐gatekeeper in mesoporous silica nanoparticles as a targeted drug delivery platform

L Palanikumar, ES Choi, JY Cheon… - Advanced Functional …, 2015 - Wiley Online Library
Selective targeting of tumor cells and release of drug molecules inside the tumor
microenvironment can reduce the adverse side effects of traditional chemotherapeutics …

Charge-controlled nanoprecipitation as a modular approach to ultrasmall polymer nanocarriers: making bright and stable nanoparticles

A Reisch, A Runser, Y Arntz, Y Mely, AS Klymchenko - Acs Nano, 2015 - ACS Publications
Ultrasmall polymer nanoparticles are rapidly gaining importance as nanocarriers for drugs
and contrast agents. Here, a straightforward modular approach to efficiently loaded and …

pH-Responsive amphiphilic polyether micelles with superior stability for smart drug delivery

I Son, Y Lee, J Baek, M Park, D Han, SK Min… - …, 2021 - ACS Publications
Despite widespread interest in the amphiphilic polymeric micelles for drug delivery systems,
it is highly desirable to achieve high loading capacity and high efficiency to reduce the side …

Self-assembled hybrid nanostructures: versatile multifunctional nanoplatforms for cancer diagnosis and therapy

M Li, Z Luo, Y Zhao - Chemistry of Materials, 2018 - ACS Publications
Self-assembled organic–inorganic hybrids are a class of promising nanomaterials
possessing interesting physiochemical and biological characteristics, making them highly …

Biocompatible reduction-responsive polypeptide micelles as nanocarriers for enhanced chemotherapy efficacy in vitro

J Ding, J Chen, D Li, C Xiao, J Zhang, C He… - Journal of Materials …, 2013 - pubs.rsc.org
To develop biocompatible reduction-responsive micellar systems for efficient intracellular
drug delivery, disulfide-linked block copolymers of methoxyl poly (ethylene glycol)(mPEG) …