Lysine acetylation is a widespread and versatile protein post-translational modification.
Lysine acetyltransferases and lysine deacetylases catalyse the addition or removal …

Background Systemic low-grade inflammation observed in diet-induced obesity has been
associated with dysbiosis and disturbance of intestinal homeostasis. This latter relies on an …

CD36, located on the cell membrane, transports fatty acids in response to dietary fat. It is a
critical fatty acid sensor and regulator of lipid metabolism. The interaction between CD36 …

Background & Aims The circadian clock orchestrates∼ 24-hour oscillations of
gastrointestinal epithelial structure and function that drive diurnal rhythms in gut microbiota …

Intestinal environment disorder is a potential pathological mechanism of obesity. There is
increasing evidence that disorders in the homeostasis of the intestinal environment can …

The acetylation of histone and non-histone proteins has been implicated in several disease
states. Modulation of such epigenetic modifications has therefore made histone …

Hickory (Carya cathayensis) nuts contain higher amount of lipids, and possess high
nutritional value and substantial health benefits. However, their lipid composition and …

Sepsis is one common cause of acute lung injury (ALI) and acute respiratory distress
syndrome (ARDS), which is closely associated with high mortality in intensive care units …

The metabolic effects of endocrine-disrupting chemicals, such as bisphenol analogues,
have drawn increasing attention. Bisphenol A (BPA) usage is associated with the …

Tuft cells in mucosal tissues are key regulators of type 2 immunity. Here, we examined the
impact of the microbiota on tuft cell biology in the intestine. Succinate induction of tuft cells …