Lipids have essential biological functions in the body (eg, providing energy storage, acting
as a signaling molecule, and being a structural component of membranes); however, an …

Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most
clinical settings. Cancer is a systemic disease that induces many functional and …

The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly
killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis …

Over the past decade, the study of metabolic abnormalities in cancer cells has risen
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …

Cancer immunotherapy can confer durable benefit, but the percentage of patients who
respond to this approach remains modest. The ability to concentrate immunostimulatory …

Simple Summary Innate immune natural killer (NK) cells are capable of killing metastatic
cancer cells without activation by antigen-presenting cells beforehand. The cytotoxic effects …

Myeloid-derived suppressor cells (MDSCs) contribute to the induction of an immune
suppressive/anergic, tumor permissive environment. MDSCs act as immunosuppression …

Natural Killer (NK) cells are innate immune responders critical for viral clearance and
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …

Background Cancer surgery is necessary and life-saving. However, the majority of patients
develop postoperative recurrence and metastasis, which are the main causes of cancer …

Surgical resection remains the mainstay treatment for solid cancers, especially for localized
disease. However, the postoperative immunosuppression provides a window for cancer cell …