[HTML][HTML] The hearing hippocampus
The hippocampus has a well-established role in spatial and episodic memory but a broader
function has been proposed including aspects of perception and relational processing …
function has been proposed including aspects of perception and relational processing …
Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia
GW Crabtree, JA Gogos - Frontiers in synaptic neuroscience, 2014 - frontiersin.org
Synaptic plasticity alters the strength of information flow between presynaptic and
postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic …
postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic …
Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus
M Roceri, W Hendriks, G Racagni, BA Ellenbroek… - Molecular …, 2002 - nature.com
It is well accepted that events that interfere with the normal program of neuronal
differentiation and brain maturation may be relevant for the etiology of psychiatric disorders …
differentiation and brain maturation may be relevant for the etiology of psychiatric disorders …
Ketamine and its metabolite (2R, 6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit
N Yao, O Skiteva, X Zhang, P Svenningsson… - Molecular …, 2018 - nature.com
Low doses of ketamine trigger rapid and lasting antidepressant effects after one injection in
treatment-resistant patients with major depressive disorder. Modulation of AMPA receptors …
treatment-resistant patients with major depressive disorder. Modulation of AMPA receptors …
Social isolation in rats: Effects on animal welfare and molecular markers for neuroplasticity
V Begni, A Sanson, N Pfeiffer, C Brandwein, D Inta… - PloS one, 2020 - journals.plos.org
Early life stress compromises brain development and can contribute to the development of
mental illnesses. A common animal model used to study different facets of psychiatric …
mental illnesses. A common animal model used to study different facets of psychiatric …
Beyond NMDA receptors: Homeostasis at the glutamate tripartite synapse and its contributions to cognitive dysfunction in schizophrenia
H Bauminger, I Gaisler-Salomon - International Journal of Molecular …, 2022 - mdpi.com
Cognitive deficits are core symptoms of schizophrenia but remain poorly addressed by
dopamine-based antipsychotic medications. Glutamate abnormalities are implicated in …
dopamine-based antipsychotic medications. Glutamate abnormalities are implicated in …
Hippocampal–prefrontal coherence mediates working memory and selective attention at distinct frequency bands and provides a causal link between schizophrenia …
Increased fronto-temporal theta coherence and failure of its stimulus-specific modulation
have been reported in schizophrenia, but the psychological correlates and underlying …
have been reported in schizophrenia, but the psychological correlates and underlying …
Treating the synapse in major psychiatric disorders: the role of postsynaptic density network in dopamine-glutamate interplay and psychopharmacologic drugs …
Dopamine-glutamate interplay dysfunctions have been suggested as pathophysiological
key determinants of major psychotic disorders, above all schizophrenia and mood disorders …
key determinants of major psychotic disorders, above all schizophrenia and mood disorders …
Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability
MP Coba, MJ Ramaker, EV Ho, SL Thompson… - Scientific reports, 2018 - nature.com
The scaffold protein DLGAP1 is localized at the post-synaptic density (PSD) of glutamatergic
neurons and is a component of supramolecular protein complexes organized by PSD95 …
neurons and is a component of supramolecular protein complexes organized by PSD95 …
The effects of arousal on apical amplification and conscious state
Neocortical pyramidal cells can integrate two classes of input separately and use one to
modulate response to the other. Their tuft dendrites are electrotonically separated from basal …
modulate response to the other. Their tuft dendrites are electrotonically separated from basal …