[HTML][HTML] The hearing hippocampus

AJ Billig, M Lad, W Sedley, TD Griffiths - Progress in neurobiology, 2022 - Elsevier
The hippocampus has a well-established role in spatial and episodic memory but a broader
function has been proposed including aspects of perception and relational processing …

Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia

GW Crabtree, JA Gogos - Frontiers in synaptic neuroscience, 2014 - frontiersin.org
Synaptic plasticity alters the strength of information flow between presynaptic and
postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic …

Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus

M Roceri, W Hendriks, G Racagni, BA Ellenbroek… - Molecular …, 2002 - nature.com
It is well accepted that events that interfere with the normal program of neuronal
differentiation and brain maturation may be relevant for the etiology of psychiatric disorders …

Ketamine and its metabolite (2R, 6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit

N Yao, O Skiteva, X Zhang, P Svenningsson… - Molecular …, 2018 - nature.com
Low doses of ketamine trigger rapid and lasting antidepressant effects after one injection in
treatment-resistant patients with major depressive disorder. Modulation of AMPA receptors …

Social isolation in rats: Effects on animal welfare and molecular markers for neuroplasticity

V Begni, A Sanson, N Pfeiffer, C Brandwein, D Inta… - PloS one, 2020 - journals.plos.org
Early life stress compromises brain development and can contribute to the development of
mental illnesses. A common animal model used to study different facets of psychiatric …

Beyond NMDA receptors: Homeostasis at the glutamate tripartite synapse and its contributions to cognitive dysfunction in schizophrenia

H Bauminger, I Gaisler-Salomon - International Journal of Molecular …, 2022 - mdpi.com
Cognitive deficits are core symptoms of schizophrenia but remain poorly addressed by
dopamine-based antipsychotic medications. Glutamate abnormalities are implicated in …

Hippocampal–prefrontal coherence mediates working memory and selective attention at distinct frequency bands and provides a causal link between schizophrenia …

AM Bygrave, T Jahans-Price, AR Wolff… - Translational …, 2019 - nature.com
Increased fronto-temporal theta coherence and failure of its stimulus-specific modulation
have been reported in schizophrenia, but the psychological correlates and underlying …

Treating the synapse in major psychiatric disorders: the role of postsynaptic density network in dopamine-glutamate interplay and psychopharmacologic drugs …

C Tomasetti, F Iasevoli, EF Buonaguro… - International Journal of …, 2017 - mdpi.com
Dopamine-glutamate interplay dysfunctions have been suggested as pathophysiological
key determinants of major psychotic disorders, above all schizophrenia and mood disorders …

Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

MP Coba, MJ Ramaker, EV Ho, SL Thompson… - Scientific reports, 2018 - nature.com
The scaffold protein DLGAP1 is localized at the post-synaptic density (PSD) of glutamatergic
neurons and is a component of supramolecular protein complexes organized by PSD95 …

The effects of arousal on apical amplification and conscious state

WA Phillips, ME Larkum, CW Harley… - Neuroscience of …, 2016 - academic.oup.com
Neocortical pyramidal cells can integrate two classes of input separately and use one to
modulate response to the other. Their tuft dendrites are electrotonically separated from basal …