As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides
both physical support and signaling regulation to cells. Some ECM molecules provide a …

In vitro multilayered tissues with mimetic architectures resembling native tissues are
valuable tools for application in medical research. In this study, an advanced bioprinting …

We studied the three-dimensional cell-extracellular matrix interactions of endothelial cells
that form multicellular structures called sprouts. We analyzed the data collected in-situ from …

Advances in mechanobiology have suggested that physiological and pathological
angiogenesis may be differentiated based on the ways in which the cells interact with the …

目的显微光学成像有景深小和易模糊等缺陷, 很难根据几何光学中的点扩散函数准确评估图像的
模糊程度, 进而很难计算景物深度. 同时, 传统的使用边缘检测算子衡量图像模糊程度变化的方法 …

The ability to manipulate magnetic particles selectively and simultaneously (within a group
of such particles) has significant implications in studying cellular behaviors and in …

The point spread function (PSF) is the main index used to evaluate the imaging resolution
and further improve the quality of an optical image. Its measurement is significant for system …

Mechanical properties of the extracellular matrix (ECM) have been observed to influence the
behavior of cells. Investigations on such an influence commonly rely on using soluble cues …

The phenomenon of continuous out-of-focus imaging often occurs in high-magnification
optical microscopy when observing large-scale targets. Lacking of accurate depth-varying …

Nowadays, the ability to pattern surfaces on the micro-and nano-scale is the basis for a wide
range of research fields. Over last few decades, a certain number of processing …