Decoding the role of miRNAs in oral cancer pathogenesis: A focus on signaling pathways

AS Doghish, AA El-Husseiny, EG Khidr… - … -Research and Practice, 2023 - Elsevier
Oral cancer (OC) is the predominant type originating in the head and neck region. The
incidence of OC is mostly associated with behavioral risk factors, including tobacco smoking …

Emerging cell cycle related non-coding RNA biomarkers from saliva and blood for oral squamous cell carcinoma

A Kalmatte, PD Rekha, CK Ratnacaram - Molecular Biology Reports, 2023 - Springer
The unnotified or undifferentiable early stages of oral squamous cell carcinoma (OSCC)
progression are the prime reasons for late-stage detection and poor survival outcomes of …

Salivary Extracellular Vesicles: Biomarkers and Beyond in Human Diseases

J Wu, G Liu, R Jia, J Guo - International Journal of Molecular Sciences, 2023 - mdpi.com
Extracellular vesicles, as bioactive molecules, have been extensively studied. There are
abundant studies in the literature on their biogenesis, secretion, structure, and content, and …

Differential Expression of MicroRNA MiR-145 and MiR-155 Downstream Targets in Oral Cancers Exhibiting Limited Chemotherapy Resistance

C Belnap, T Divis, K Kingsley, KM Howard - International Journal of …, 2024 - mdpi.com
New evidence has suggested that non-coding microRNAs play a significant role in
mediating and modulating chemotherapy resistance, particularly among oral cancers. One …

[HTML][HTML] Salivary exosomal microRNAs as biomonitoring tool for diagnosis and prognosis of patients with head and neck squamous cell carcinoma: a systematic …

L Sanesi, G Mori, G Troiano, A Ballini, F Valzano… - Archives of Oral …, 2024 - Elsevier
Objective Exosomes are extracellular vesicles found in saliva and other body fluids. These
vesicles range in size from 30 to 150 nm and play a crucial role in intercellular …

Sample‐to‐answer salivary miRNA testing: New frontiers in point‐of‐care diagnostic technologies

Z Zhang, T Liu, M Dong, MA Ahamed… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Abstract MicroRNA (miRNA), crucial non‐coding RNAs, have emerged as key biomarkers in
molecular diagnostics, prognosis, and personalized medicine due to their significant role in …

[HTML][HTML] Expression Analysis of Circulating microRNAs in Saliva and Plasma for the Identification of Clinically Relevant Biomarkers for Oral Squamous Cell Carcinoma …

F Rocchetti, G Tenore, F Macali, T Vicidomini… - Cancers, 2024 - mdpi.com
Simple Summary In recent years, liquid biopsy has been introduced as a new method for the
detection and management of cancer, but the studies on oral squamous cell carcinoma …

Metastasis and Cell Proliferation Inhibition by MicroRNAs and its Potential Therapeutic Applications in OSCC: A Systematic Review

SM Malekjafarian, N Mohtasham, M Mirhashemi… - … -Research and Practice, 2024 - Elsevier
Abstract Background and Aims Oral squamous cell carcinoma (OSCC) is among the most
malignant cancers in the world and has a high mortality rate. MicroRNAs (miRNAs) have …

The simultaneous miR-155-5p overexpression and miR-223-3p inhibition can activate pEMT in oral squamous cell carcinoma

R Zhou, Z Chen, Y Cai, H Zhang, S Mao… - Journal of Applied Oral …, 2024 - SciELO Brasil
Objective This study aims to explore the effects of miR-223-3p and miR-155-5p on epithelial-
mesenchymal transition (EMT) and migration in oral squamous cell carcinoma (OSCC) …

外泌体微小RNA 在口腔鳞状细胞癌中的研究进展

王菁, 徐文华 - 口腔医学研究, 2024 - manu45.magtech.com.cn
外泌体作为一种细胞外囊泡(extracellular vesicle, EVs), 已在多项研究中被证明为是细胞间通讯
的重要介质. 在肿瘤疾病中, 存在于肿瘤微环境中的各类细胞产生的外泌体能够装载数量异常的 …