Glycan-based biomarkers for mucopolysaccharidoses

R Lawrence, JR Brown, F Lorey, PI Dickson… - Molecular genetics and …, 2014 - Elsevier
The mucopolysaccharidoses (MPS) result from attenuation or loss of enzyme activities
required for lysosomal degradation of the glycosaminoglycans, hyaluronan, heparan sulfate …

Extraction, isolation and analysis of chondroitin sulfate glycosaminoglycans

T Nakano, M Betti, Z Pietrasik - Recent Patents on Food …, 2010 - ingentaconnect.com
Glycosaminoglycans (GAGs) including chondroitin sulfate (CS) and chondroitin
sulfate/dermatan sulfate (CS/DS) copolymers are anionic straight chain polysaccharides …

[HTML][HTML] Macrophages bind LDL using heparan sulfate and the perlecan protein core

C Ng, JM Whitelock, H Williams, HN Kim… - Journal of Biological …, 2021 - ASBMB
The retention of low-density lipoprotein (LDL) is a key process in the pathogenesis of
atherosclerosis and largely mediated via smooth-muscle cell-derived extracellular …

[HTML][HTML] Enzymatic production of chondroitin oligosaccharides and its sulfate derivatives

W Zhang, R Xu, X Jin, Y Wang, L Hu… - … in Bioengineering and …, 2022 - frontiersin.org
Chondroitin sulfate (CS) has a wide range of physiological functions and clinical
applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate …

Chicken leg bone as a source of chondroitin sulfate

X Wang, Q Shen, C Zhang, W Jia, L Han, Q Yu - Carbohydrate polymers, 2019 - Elsevier
In this work, chondroitin sulfate (CS) was extracted from chicken leg bone soup using the
heat-resin static adsorption extraction (HSAE) method. The HSAE method was optimized as …

Biocompatibility and structural characterization of glycosaminoglycans isolated from heads of silver-banded whiting (Sillago argentifasciata Martin & Montalban 1935)

BF Ticar, Z Rohmah, TAN Neri, IG Pahila… - International journal of …, 2020 - Elsevier
Glycosaminoglycans (GAGs) were extracted from heads of silver-banded whiting (SBW) fish
and subjected to preliminary biocompatibility testing per ISO 10993: intracutaneous irritation …

Review on complement analysis method and the roles of glycosaminoglycans in the complement system

L Li, Y Li, M Ijaz, M Shahbaz, Q Lian, F Wang - Carbohydrate polymers, 2015 - Elsevier
Complement system is composed of over 30 proteins and it plays important roles in self-
defence and inflammation. There are three activation pathways, including classical pathway …

A rapid method for extraction, purification and structure analysis of chondroitin sulfate from six marine tissues

Y Wang, S Ahmadi, C Yu, L Zhang, X Hu… - Food Quality and …, 2022 - academic.oup.com
This study was designed to establish a strategy for the extraction, purification, and structure
analysis of chondroitin sulfate (CS) in milligram amounts. Crude acidic polysaccharides …

[HTML][HTML] Structure-activity relationships of bioengineered heparin/heparan sulfates produced in different bioreactors

HN Kim, JM Whitelock, MS Lord - Molecules, 2017 - mdpi.com
Heparin and heparan sulfate are structurally-related carbohydrates with therapeutic
applications in anticoagulation, drug delivery, and regenerative medicine. This study …

Identification of chondroitin‐like molecules from biofilm isolates Exiguobacterium indicum A11 and Lysinibacillus sp. C13

DU Bhotmange, RS Singhal - Journal of Applied Microbiology, 2015 - academic.oup.com
Aims The study aims to investigate whether the bacteria from biofilms can produce
chondroitin‐like molecules (CLMs). Methods and Results Chondroitin belongs to the class of …