Azadirachta indica L. is a multipurpose medicinal tree of family Meliaceae. It occurs in
tropical and semitropical regions of the world. Different parts of this miraculous tree are used …

This review covers the isolation and structure determination of limonoids reported during
2014–2016 (with 363 new compounds in 68 papers), together with the relevant biological …

Triterpenes with complex scaffold modifications are widespread in the plant kingdom.
Limonoids are an exemplary family that are responsible for the bitter taste in citrus (eg …

Human pancreatic α-amylase (HPA) inhibitors offer an effective strategy to lower
postprandial hyperglycemia via control of starch breakdown. Limonoids from Azadirachta …

Background Breast cancer is one of the most commonly diagnosed invasive cancers among
women around the world. Among several subtypes, triple negative breast cancer (TNBC) is …

Tau is a phosphoprotein with natively unfolded conformation that functions to stabilize
microtubules in axons. Alzheimer's disease pathology triggers several modifications in tau …

The Alzheimer's disease pathology is associated with accumulation of intracellular
neurofibrillary tangles and extracellular senile plaques. The formation of initial nucleus …

Abstract Background Neem tree (Azadirachta indica) is one of the richest sources of
skeletally diverse triterpenoids and they are well-known for their broad-spectrum …

Background Neem tree serves as a cornucopia for triterpenoids called limonoids that are of
profound interest to humans due to their diverse biological activities. However, the …

Neem (Azadirachta indica L.) is well known for its medicinal, agricultural, and pesticidal
applications since ages. The secondary metabolites, limonoids, confer these biological …