An overview of spirooxindole as a promising scaffold for novel drug discovery
LM Zhou, RY Qu, GF Yang - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction: Spirooxindole, a unique and versatile scaffold, has been widely studied in
some fields such as pharmaceutical chemistry and synthetic chemistry. Especially in the …
some fields such as pharmaceutical chemistry and synthetic chemistry. Especially in the …
[HTML][HTML] Synthesis of biologically active molecules through multicomponent reactions
Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …
significant role that multicomponent reactions (MCRs) have played as a very important tool …
[HTML][HTML] Spirooxindole: a versatile biologically active heterocyclic scaffold
Spirooxindoles occupy an important place in heterocyclic chemistry. Many natural
spirooxindole-containing compounds have been identified as bio-promising agents …
spirooxindole-containing compounds have been identified as bio-promising agents …
The application of isatin-based multicomponent-reactions in the quest for new bioactive and druglike molecules
Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …
they display vast biological activities. Recent efforts concerning the preparation of oxindole …
Synthetic strategies and pharmacological activities of chromene and its derivatives: An overview
MK Katiyar, GK Dhakad, S Arora, S Bhagat… - Journal of Molecular …, 2022 - Elsevier
Chromene is commonly found in nature and is considered one of the most frequently used
scaffolds in heterocyclic chemistry for the designing of chemical probes for therapeutic and …
scaffolds in heterocyclic chemistry for the designing of chemical probes for therapeutic and …
Recent advances with alkaline phosphatase isoenzymes and their inhibitors
DM Zaher, MI El‐Gamal, HA Omar… - Archiv der …, 2020 - Wiley Online Library
Alkaline phosphatases are found in different living species and play crucial roles in various
significant functions, such as hydrolyzing a variable spectrum of phosphate‐containing …
significant functions, such as hydrolyzing a variable spectrum of phosphate‐containing …
Anticancer potential of spirocompounds in medicinal chemistry: A pentennial expedition
D Bora, A Kaushal, N Shankaraiah - European Journal of Medicinal …, 2021 - Elsevier
Spirocompounds constitute an important class of organic frameworks enveloping numerous
pharmacological activities, among them, the promising anticancer potential of …
pharmacological activities, among them, the promising anticancer potential of …
Engaging isatins in multicomponent reactions (MCRs)–easy access to structural diversity
Multicomponent reactions (MCRs) are a valuable tool in diversity‐oriented synthesis. Its
application to privileged structures is gaining relevance in the fields of organic and …
application to privileged structures is gaining relevance in the fields of organic and …
Synthesis, characterization of phyto-functionalized CuO nano photocatalysts for mitigation of textile dyes in waste water purification, antioxidant, anti-inflammatory and …
KM Navada, N G. K, JN D'Souza, S Kouser, M D. J - Applied Nanoscience, 2021 - Springer
In this scientific paper we report, cost-effective synthesis of unique copper oxide
nanoparticles (CPC NPs) coupled with properties from phytocompounds of Pouteria …
nanoparticles (CPC NPs) coupled with properties from phytocompounds of Pouteria …
Steering the antitumor drug discovery campaign towards structurally diverse indolines
A Thakur, A Singh, N Kaur, R Ojha, K Nepali - Bioorganic Chemistry, 2020 - Elsevier
Indoline framework is often perpended as a privileged heterocycle present in medicinally
valuable compounds of natural and synthetic origin. This review article presents the rational …
valuable compounds of natural and synthetic origin. This review article presents the rational …