Conventional oxygen therapy (COT) and noninvasive ventilation (NIV) have been
considered for decades as frontline treatment for acute or chronic respiratory failure …

The use of trans-nasal pulmonary aerosol delivery via high-flow nasal cannula (HFNC) has
expanded in recent years. However, various factors influencing aerosol delivery in this …

Background The efficacy and safety of high flow nasal therapy (HFNT) in patients with acute
hypercapnic exacerbation of chronic obstructive pulmonary disease (AECOPD) are unclear …

Rationale: The long-term effects of using a high-flow nasal cannula for chronic hypercapnic
respiratory failure caused by chronic obstructive pulmonary disease remain unclear …

High-flow nasal cannula (HFNC) is extensively used for acute respiratory failure. However,
questions remain regarding its physiological effects. We explored 1) whether HFNC …

Background Whether respiratory efforts and their timing can be reliably detected during
pressure support ventilation using standard ventilator waveforms is unclear. This would give …

Objective To evaluate the clinical efficacy of high-flow nasal oxygen therapy (HFNC) and
non-invasive ventilation (NIV) in patients with acute exacerbation of chronic obstructive …

Purpose This study aimed to evaluate the clinical outcomes of high-flow nasal cannula
(HFNC) compared with conventional oxygen therapy (COT) in patients with hypercapnic …

Exacerbations are part of the natural history of chronic obstructive pulmonary disease and
asthma. Severe exacerbations can cause acute respiratory failure, which may ultimately …

Background High-flow nasal cannula (HFNC) and noninvasive ventilation (NIV) have been
used for the treatment of COPD and respiratory failure in clinical settings. We aimed to …