Cancer cachexia is a multifactorial, paraneoplastic syndrome that impacts roughly half of all
cancer patients. It can negatively impact patient quality of life and prognosis by causing …

Cancer-associated cachexia (CC) is a pathological condition characterized by sarcopenia,
adipose tissue depletion, and progressive weight loss. CC is driven by multiple factors such …

Background The naturally occurring amino acid 5-aminolevulinic acid (5-ALA) is a precursor
of protoporphyrin IX (PpIX) biosynthesised in the mitochondria. When accumulated PpIX is …

The development of drug delivery systems for use in the treatment of cardiovascular
diseases is an area of great interest. We report herein on an evaluation of the therapeutic …

Chinese herbal medicines have multiple targets and properties, and their use in
multidisciplinary cancer therapies has consequently received increasing attention. Here, we …

Although gemcitabine (GEM) is widely used in chemotherapy for pancreatic ductal
adenocarcinoma (PDA), drug resistance restricts its clinical effectiveness. To examine the …

Significance Two of the leading causes of death worldwide are cancer and cardiovascular
diseases. Most cancer patients suffer from a metabolic wasting syndrome known as cancer …

Cancer cachexia is a syndrome of progressive weight loss and muscle wasting occurring in
many advanced cancer patients. Cachexia significantly impairs quality of life and increases …

Pterostilbene (PTE) is a natural sterbenoid contained in blueberries that has an antioxidant
effect. In contrast, PTE also generates oxidative stress in cancer cells and provides an …

Background Parkinson's disease (PD), the most prevalent type of Parkinsonism, is a
progressive neurological condition characterized by a range of motor and non‐motor …