Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased
insulin activity and/or insulin secretion. Pathological changes such as nephropathy …

Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that govern the
expression of genes responsible for energy metabolism, cellular development, and …

Since 1985, the thiazolidinedione pioglitazone has been widely used as an insulin
sensitizer drug for type 2 diabetes mellitus (T2DM). Although fluid retention was early …

Liver disease is the spectrum of liver damage ranging from simple steatosis called as
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …

Simple Summary Alpelisib is a drug used to treat breast cancer that has certain
characteristics (hormone receptor-positive (HR+), human epidermal growth receptor 2 …

Recent evidence relating to the impact of COVID-19 on people with diabetes is limited but
continues to emerge. COVID-19 pneumonia is a newly identified illness spreading rapidly …

В настоящем издании проанализированы и систематизированы сведения по
клиническому применению лекарственных средств, для которых гепатотропное …

Mushrooms belong to the family “Fungi” and became famous for their medicinal properties
and easy accessibility all over the world. Because of its pharmaceutical properties, including …

Objective The use of thiazolidinediones (TZDs) as insulin sensitizers has been shown to
have side effects including increased accumulation of bone marrow adipocytes (BMAds) …