Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

[HTML][HTML] Combining copper and zinc into a biosensor for anti-chemoresistance and achieving osteosarcoma therapeutic efficacy

YY Lim, AMA Zaidi, A Miskon - Molecules, 2023 - mdpi.com
Due to its built-up chemoresistance after prolonged usage, the demand for replacing
platinum in metal-based drugs (MBD) is rising. The first MBD approved by the FDA for …

[HTML][HTML] Long non-coding RNAs as emerging targets in lung cancer

J Gencel-Augusto, W Wu, TG Bivona - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (LncRNAs) are non-protein coding molecules
longer than 200 nucleotides. They play essential roles in normal cell function and …

RNA-cleaving DNAzymes for accurate biosensing and gene therapy

X Gao, Y Liu, W Huo, Y Song, Y Chen, J Zhang, X Yang… - Nanoscale, 2023 - pubs.rsc.org
RNA-cleaving DNAzymes, which are single-stranded catalytic DNA, have attracted
considerable attention in bioanalysis and biomedical applications because of their high …

[HTML][HTML] Role of long non-coding RNA in chemoradiotherapy resistance of nasopharyngeal carcinoma

Y Yang, QP Yuan, W Tang, Y Ma, JY Duan… - Frontiers in …, 2024 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the
nasopharyngeal epithelial cells. Common treatment methods for NPC include radiotherapy …

SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis

S Li, W Xu, Y Yin, H Wei, K Li, M Xie, F Lv, L Xie, B Hu - Apoptosis, 2024 - Springer
Oxaliplatin resistance poses a significant challenge in colorectal cancer (CRC) therapy,
necessitating further investigation into the underlying molecular mechanisms. This study …

[HTML][HTML] Long non-coding RNAs in drug resistance across the top five cancers: Update on their roles and mechanisms

Y Shi, J Adu-Amankwaah, Q Zhao, X Li, Q Yu, A Bushi… - Heliyon, 2024 - cell.com
Cancer drug resistance stands as a formidable obstacle in the relentless fight against the top
five prevalent cancers: breast, lung, colorectal, prostate, and gastric cancers. These …

Evaluation of miRNA 130a-3P and miRNA 301a-3P in Egyptian patients with urinary bladder carcinoma

EM Abd El Gayed, MAF Hamouda, SM Elsobky… - Human Gene, 2024 - Elsevier
Objectives To study the role of microRNA 130a-3p and microRNA 301a-3p in urinary
bladder carcinoma. Background Despite the discovery of several clinical and molecular …

[HTML][HTML] Evaluating Ovarian Cancer Chemotherapy Response Using Gene Expression Data and Machine Learning

S Amniouel, K Yalamanchili, S Sankararaman… - …, 2024 - mdpi.com
Background: Ovarian cancer (OC) is the most lethal gynecological cancer in the United
States. Among the different types of OC, serous ovarian cancer (SOC) stands out as the most …

Transcriptomic Analysis Reveals Early Alterations Associated with Intrinsic Resistance to Target Therapy in Lung Adenocarcinoma Cell Lines

M Perez-Medina, JS Lopez-Gonzalez, JJ Benito-Lopez… - 2024 - preprints.org
Lung adenocarcinoma is the most prevalent form of lung cancer, and drug resistance is a
significant obstacle in its treatment. This study aimed to investigate the overexpression of …