Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia/reperfusion injury via suppressing GPX4-mediated ferroptosis

J Guo, Z Song, J Yu, C Li, C Jin, W Duan, X Liu… - Cell Death & …, 2022 - nature.com
Abstract Ischemia/reperfusion (I/R)-induced liver injury with severe cell death is a major
complication of liver transplantation. Transmembrane member 16A (TMEM16A), a …

[HTML][HTML] Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice

JK Truong, J Li, Q Li, K Pachura, A Rao, S Gumber… - JCI insight, 2023 - ncbi.nlm.nih.gov
The pronounced choleretic properties of 24-norUrsodeoxycholic acid (norUDCA) to induce
bicarbonate-rich bile secretion have been attributed to its ability to undergo cholehepatic …

Human induced pluripotent stem cell based hepatic-modeling of lipid metabolism associated TM6SF2 E167K variant

LAP Faccioli, Y Sun, O Animasahun, T Motomura… - Hepatology, 2023 - journals.lww.com
This work was supported by NIH grants DK099257 to AS-G and DN, TR003289, DK096990,
DK117881, DK119973, TR002383 to AS-G and DK135606 to AS-G and MTM This work was …

[PDF][PDF] Charting the explicit path: Translational dynamics of hepatic bioengineering from experimental benchmarks to practical bedside applications. Medliber Regener …

S Radhakrishnan, CA Martin… - … and Mohamed Rela1, 2024 - backend.medliber.com
Liver transplantation is the only optimal method used for treating endstage liver disease,
originated in 1957 and was developed as a mainstream methodology over a span of two …

[PDF][PDF] Charting the explicit path: Translational dynamics of hepatic bioengineering from experimental benchmarks to practical bedside applications. Medliber Regener …

S Radhakrishnan, CA Martin… - Catherine Ann Martin1 …, 2023 - researchgate.net
Liver transplantation is the only optimal method used for treating endstage liver disease,
originated in 1957 and was developed as a mainstream methodology over a span of two …