Shaping the brain vasculature in development and disease in the single-cell era
T Wälchli, J Bisschop, P Carmeliet, G Zadeh… - Nature Reviews …, 2023 - nature.com
The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …
Critical roles of protein arginine methylation in the central nervous system
K Chang, D Gao, J Yan, L Lin, T Cui, S Lu - Molecular Neurobiology, 2023 - Springer
A remarkable post-transitional modification of both histones and non-histone proteins is
arginine methylation. Methylation of arginine residues is crucial for a wide range of cellular …
arginine methylation. Methylation of arginine residues is crucial for a wide range of cellular …
[HTML][HTML] An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma
Characterized by intracellular lipid droplet accumulation, clear cell renal cell carcinoma
(ccRCC) is resistant to cytotoxic chemotherapy and is a lethal disease. Through an unbiased …
(ccRCC) is resistant to cytotoxic chemotherapy and is a lethal disease. Through an unbiased …
CCIVR2 facilitates comprehensive identification of both overlapping and non-overlapping antisense transcripts within specified regions
M Suzuki, S Sakai, K Ota, Y Bando, C Uchida… - Scientific Reports, 2023 - nature.com
Pairs of sense and antisense transcriptions that are adjacent at their 5′ and 3′ regions are
called divergent and convergent transcription, respectively. However, the structural …
called divergent and convergent transcription, respectively. However, the structural …
Hemodynamics regulate spatiotemporal artery muscularization in the developing circle of Willis
Vascular smooth muscle cells (VSMCs) envelop vertebrate brain arteries and play a crucial
role in regulating cerebral blood flow and neurovascular coupling. The dedifferentiation of …
role in regulating cerebral blood flow and neurovascular coupling. The dedifferentiation of …
Serum Interleukin-1 levels are associated with intracranial aneurysm instability
Q Liu, P Liu, Y Zhang, M Mossa-Basha… - Translational Stroke …, 2024 - Springer
Abstract Serum interleukin-1 (IL-1) are possibly indicative of the inflammation in the
intracranial aneurysm (IA) wall. This study aimed to investigate whether IL-1 could …
intracranial aneurysm (IA) wall. This study aimed to investigate whether IL-1 could …
Systematic identification of post-transcriptional regulatory modules
In our cells, a limited number of RNA binding proteins (RBPs) are responsible for all aspects
of RNA metabolism across the entire transcriptome. To accomplish this, RBPs form …
of RNA metabolism across the entire transcriptome. To accomplish this, RBPs form …
A future blood test to detect cerebral aneurysms
Intracranial aneurysms are reported to affect 2–5% of the population. Despite advances in
the surgical management of this disease, diagnostic technologies have marginally improved …
the surgical management of this disease, diagnostic technologies have marginally improved …
Influence of humanized nursing on patients with intracranial aneurysm subarachnoid hemorrhage undergoing interventional embolization
G Waili, S Amuti - Heliyon, 2023 - cell.com
Objective To investigate the effect of nursing intervention on patients with intracranial
aneurysm subarachnoid hemorrhage who underwent interventional embolization. Methods …
aneurysm subarachnoid hemorrhage who underwent interventional embolization. Methods …
MicroRNA-451 Regulates Angiogenesis in Intracerebral Hemorrhage by Targeting Macrophage Migration Inhibitory Factor
S Bai, G Zhang, S Chen, X Wu, J Li, J Wang… - Molecular …, 2024 - Springer
Intracerebral hemorrhage (ICH) is a subtype of stroke with the highest fatality and disability
rate. Up to now, commonly used first-line therapies have limited value in improving …
rate. Up to now, commonly used first-line therapies have limited value in improving …