Perineural invasion and associated pain in pancreatic cancer

AA Bapat, G Hostetter, DD Von Hoff, H Han - Nature Reviews Cancer, 2011 - nature.com
Perineural invasion (PNI) is a prominent characteristic of pancreatic cancer. PNI is a process
whereby cancer cells invade the surrounding nerves, thus providing an alternative route for …

Vaccine therapy for pancreatic cancer

B Salman, D Zhou, EM Jaffee, BH Edil… - Oncoimmunology, 2013 - Taylor & Francis
Pancreatic cancer is a lethal disease and currently available therapies have significant
limitations. Pancreatic cancer is thus an ideal setting for the development of novel treatment …

Axon guidance molecules promote perineural invasion and metastasis of orthotopic pancreatic tumors in mice

NR Jurcak, AA Rucki, S Muth, E Thompson, R Sharma… - Gastroenterology, 2019 - Elsevier
Background & Aims Little is known about mechanisms of perineural invasion (PNI) by
pancreatic ductal adenocarcinomas (PDAs) or other tumors. Annexin A2 (ANXA2) regulates …

[HTML][HTML] Image-guided surgery in patients with pancreatic cancer: first results of a clinical trial using SGM-101, a novel carcinoembryonic antigen-targeting, near …

CES Hoogstins, LSF Boogerd… - Annals of surgical …, 2018 - Springer
Background Near-infrared (NIR) fluorescence is a promising novel imaging technique that
can aid in intraoperative demarcation of pancreatic cancer (PDAC) and thus increase radical …

Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy

RL Sleightholm, BK Neilsen, J Li, MM Steele… - Pharmacology & …, 2017 - Elsevier
Chemokine networks regulate a variety of cellular, physiological, and immune processes.
These normal functions can become appropriated by cancer cells to facilitate a more …

Histologic grading of the extent of residual carcinoma following neoadjuvant chemoradiation in pancreatic ductal adenocarcinoma: a predictor for patient outcome

D Chatterjee, MH Katz, A Rashid, GR Varadhachary… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Several grading schemes for the extent of residual tumor in posttreatment
pancreaticoduodenectomy (PD) specimens have been proposed. However, the prognostic …

[HTML][HTML] Preoperative radiochemotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer (PREOPANC trial): study protocol for a …

E Versteijne, CHJ van Eijck, CJA Punt, M Suker… - Trials, 2016 - Springer
Background Pancreatic cancer is the fourth largest cause of cancer death in the United
States and Europe with over 100,000 deaths per year in Europe alone. The overall 5-year …

Perineural and intraneural invasion in posttherapy pancreaticoduodenectomy specimens predicts poor prognosis in patients with pancreatic ductal adenocarcinoma

D Chatterjee, MH Katz, A Rashid, H Wang… - The American journal …, 2012 - journals.lww.com
Perineural invasion (PNI) is one of the established prognostic factors in pancreatic ductal
adenocarcinoma (PDAC). However, the prognostic significance of PNI in patients with PDAC …

Diffusion-weighted MR imaging of solid and cystic lesions of the pancreas

Y Wang, FH Miller, ZE Chen, L Merrick, KJ Mortele… - Radiographics, 2011 - pubs.rsna.org
Diffusion-weighted magnetic resonance (MR) imaging is increasingly used in the detection
and characterization of pancreatic lesions. Diffusion-weighted imaging may provide …

[HTML][HTML] Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704

A Manuyakorn, R Paulus, J Farrell… - Journal of Clinical …, 2010 - ncbi.nlm.nih.gov
Purpose Differences in cellular levels of histone modifications have predicted clinical
outcome in certain cancers. Here, we studied the prognostic and predictive value of three …