The vascular endothelium plays a vital role during embryogenesis and aging and is a cell
monolayer that lines the blood vessels. The immune system recognizes the endothelium as …

Fluid homeostasis is fundamental for brain function with cerebral edema and hydrocephalus
both being major neurological conditions. Fluid movement from blood into brain is one …

Emerging evidence shows that the meninges conduct essential immune surveillance and
immune defense at the brain border, and the dysfunction of meningeal immunity contributes …

Abstract Background Idiopathic Normal pressure hydrocephalus (iNPH) is a form of adult
hydrocephalus that is clinically characterized by progressive gait impairment, cognitive …

Escherichia coli continues to be the predominant Gram-negative pathogen causing neonatal
meningitis worldwide. Inflammatory mediators have been implicated in the pathogenesis of …

Glial activation is involved in neuroinflammation and blood–brain barrier (BBB) damage,
which plays a key role in ischemic stroke-induced neuronal damage; therefore, regulating …

This aim of this editorial is to highlight progress made in brain barrier and brain fluid
research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers …

Current available animal and in vitro cell-based models for studying brain-related
pathologies and drug evaluation face several limitations since they are unable to reproduce …

Stroke is a major contributor to mortality and morbidity worldwide and the most common
cause of epilepsy in the elderly in high income nations. In recent years, it has become …

Reversible cerebral vasoconstriction syndrome (RCVS) is a complex neurovascular disorder
characterized by repetitive thunderclap headaches and reversible cerebral vasoconstriction …