In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …

Article abstract MRI is very sensitive in showing MS lesions throughout the CNS. Using MRI
for diagnostic purposes, however useful, is a complex issue because of limited specificity of …

OBJECTIVE (a) To establish whether the cognitive decline of the early phase of relapsing-
remitting multiple sclerosis depends on the progression of the burden of disease, or on the …

Although the diagnosis of multiple sclerosis relies on the demonstration of disease
dissemination in space and time, the exclusion of other neurological disorders is also …

OBJECTIVE To assess the feasibility of a new technique based on diffusion anisotropy to
segment white and grey matter of the brain. To use this technique to measure the mean …

In multiple sclerosis (MS), the correlation between disability and the volume of white matter
lesions on magnetic resonance imaging (MRI) is usually weak. This may be because lesion …

Previous studies assessing the magnetic resonance imaging (MRI) correlates of cognitive
dysfunction in multiple sclerosis (MS) achieved conflicting results. Diffusion tensor (DT)-MRI …

BACKGROUND AND PURPOSE: We assessed whether the extent of macro-and
microscopic disease in the cortical and subcortical brain tissue, as revealed by MR and …

OBJECTIVES To assess (a) whether the changes in the normal appearing brain tissue
(NABT), as revealed by magnetisation transfer (MT) histogram analysis, correlates with …

In this review, we emphasize neuropathologic and neurobehavioral aspects of central
pontine and extrapontine myelinolysis (CPM/EPM), also known as the osmotic …