Maximum life span differences among animal species exceed life span variation achieved
by experimental manipulation by orders of magnitude. The differences in the characteristic …

In this review, it is our aim 1) to describe the high diversity in molecular and structural
antioxidant defenses against oxidative stress in animals, 2) to extend the traditional concept …

While ruling out programmed aging, evolutionary theory predicts a quasi-program for aging,
a continuation of the developmental program that is not turned off, is constantly on …

The main objective of this review is to provide an appraisal of the current status of the
relationship between energy intake and the life span of animals. The concept that a …

▪ Abstract Senescence (aging) is defined as a decline in performance and fitness with
advancing age. Senescence is a nearly universal feature of multicellular organisms, and …

Antioxidant enzymes perform a variety of vital functions including the reduction of life‐
shortening oxidative damage. We used the honey bee genome sequence to identify the …

The exceptional longevity of social insect queens despite their lifelong high fecundity
remains poorly understood in ageing biology. To gain insights into the mechanisms that …

Cardiotoxicity remains the number one reason for drug withdrawal from the market, and
Food and Drug Administration issued black box warnings, thus demonstrating the need for …

The oxidative stress theory of aging proposes that accumulation of oxidative damage is the
main proximate cause of aging and that lifespan is determined by the rate at which this …

Living in social groups could influence the evolution of senescence and longevity by
affecting key life‐history parameters such as extrinsic mortality and the cost of reproduction …