A review of micronutrients and the immune system–working in harmony to reduce the risk of infection

AF Gombart, A Pierre, S Maggini - Nutrients, 2020 - mdpi.com
Immune support by micronutrients is historically based on vitamin C deficiency and
supplementation in scurvy in early times. It has since been established that the complex …

Nutritional and pharmacological importance of stinging nettle (Urtica dioica L.): A review

KK Bhusal, SK Magar, R Thapa, A Lamsal, S Bhandari… - Heliyon, 2022 - cell.com
Stinging nettle (Urtica dioica L.) is a wild herbaceous perennial blooming plant that is
commonly known as stinging nettle. It's a common, multi-purpose crop that's sometimes …

Iron deficiency anaemia revisited

MD Cappellini, KM Musallam… - Journal of internal …, 2020 - Wiley Online Library
Iron deficiency anaemia is a global health concern affecting children, women and the
elderly, whilst also being a common comorbidity in multiple medical conditions. The …

Ferroptosis and cancer: mitochondria meet the “iron maiden” cell death

AM Battaglia, R Chirillo, I Aversa, A Sacco, F Costanzo… - Cells, 2020 - mdpi.com
Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …

[HTML][HTML] Targeting iron metabolism in cancer therapy

M Morales, X Xue - Theranostics, 2021 - ncbi.nlm.nih.gov
Iron is a critical component of many cellular functions including DNA replication and repair,
and it is essential for cell vitality. As an essential element, iron is critical for maintaining …

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

T Nakamura, I Naguro, H Ichijo - Biochimica et Biophysica Acta (BBA) …, 2019 - Elsevier
Background Iron is essential for many types of biological processes. However, excessive
iron can be cytotoxic and can lead to many diseases. Since ferroptosis, which is an iron …

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis

GQ Chen, FA Benthani, J Wu, D Liang… - Cell Death & …, 2020 - nature.com
The antimalarial drug artemisinin and its derivatives have been explored as potential
anticancer agents, but their underlying mechanisms are controversial. In this study, we found …

[HTML][HTML] Iron homeostasis and oxidative stress: An intimate relationship

D Galaris, A Barbouti, K Pantopoulos - Biochimica et Biophysica Acta (BBA) …, 2019 - Elsevier
Iron is a transition metal and essential constituent of almost all living cells and organisms. As
component of various metalloproteins it is involved in critical biochemical processes such as …

Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management

MD Cappellini, J Comin‐Colet… - American journal of …, 2017 - Wiley Online Library
Iron deficiency, even in the absence of anemia, can be debilitating, and exacerbate any
underlying chronic disease, leading to increased morbidity and mortality. Iron deficiency is …

Redox-and non-redox-metal-induced formation of free radicals and their role in human disease

M Valko, K Jomova, CJ Rhodes, K Kuča… - Archives of toxicology, 2016 - Springer
Transition metal ions are key elements of various biological processes ranging from oxygen
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …