A cross-talk between sestrins, chronic inflammation and cellular senescence governs the development of age-associated sarcopenia and obesity
G Livshits, A Kalinkovich - Ageing Research Reviews, 2023 - Elsevier
The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …
Adipokines at the crossroads of obesity and mesenchymal stem cell therapy
DV Pham, TK Nguyen, PH Park - Experimental & Molecular Medicine, 2023 - nature.com
Mesenchymal stem cell (MSC) therapy is an emerging treatment strategy to counteract
metabolic syndromes, including obesity and its comorbid disorders. However, its …
metabolic syndromes, including obesity and its comorbid disorders. However, its …
Using adipose‐derived mesenchymal stem cells to fight the metabolic complications of obesity: Where do we stand?
A Mikłosz, BE Nikitiuk, A Chabowski - Obesity Reviews, 2022 - Wiley Online Library
Obesity is a critical risk factor for the development of metabolic diseases, and its prevalence
is increasing worldwide. Stem cell‐based therapies have become a promising tool for …
is increasing worldwide. Stem cell‐based therapies have become a promising tool for …
Translating MSC therapy in the age of obesity
Mesenchymal stromal cell (MSC) therapy has seen increased attention as a possible option
to treat a number of inflammatory conditions including COVID-19 acute respiratory distress …
to treat a number of inflammatory conditions including COVID-19 acute respiratory distress …
[HTML][HTML] Novel anti-aging herbal formulation Jing Si displays pleiotropic effects against aging associated disorders
Common characteristics of aging include reduced somatic stem cell number, susceptibility to
cardiac injuries, metabolic imbalances and increased risk for oncogenesis. In this study …
cardiac injuries, metabolic imbalances and increased risk for oncogenesis. In this study …
Muscle and adipose tissue communicate with extracellular vesicles
S Rome - International Journal of Molecular Sciences, 2022 - mdpi.com
In numerous body locations, muscle and adipose tissue are in close contact. Both tissues
are endocrine organs that release cytokines, playing a crutial role in the control of tissue …
are endocrine organs that release cytokines, playing a crutial role in the control of tissue …
Management of obesity and obesity-related disorders: from stem cells and epigenetics to its treatment
Obesity is a complex worldwide disease, characterized by an abnormal or excessive fat
accumulation. The onset of this pathology is generally linked to a complex network of …
accumulation. The onset of this pathology is generally linked to a complex network of …
Influence of type 2 diabetes and obesity on adipose mesenchymal stem/stromal cell immunoregulation
M Mahmoud, M Abdel-Rasheed - Cell and Tissue Research, 2023 - Springer
Abstract Type 2 diabetes (T2D), associated with obesity, represents a state of metabolic
inflammation and oxidative stress leading to insulin resistance and progressive insulin …
inflammation and oxidative stress leading to insulin resistance and progressive insulin …
Gene therapy based on mesenchymal stem cells derived from adipose tissue for the treatment of obesity and its metabolic complications
M Lopez-Yus, MP García-Sobreviela… - International Journal of …, 2023 - mdpi.com
Obesity is a highly prevalent condition often associated with dysfunctional adipose tissue.
Stem cell-based therapies have become a promising tool for therapeutic intervention in the …
Stem cell-based therapies have become a promising tool for therapeutic intervention in the …
Efficacy of adipose‐derived mesenchymal stem cell therapy in the treatment of chronic micro‐and macrovascular complications of diabetes
A Mikłosz, A Chabowski - Diabetes, Obesity and Metabolism, 2024 - Wiley Online Library
Diabetes mellitus is a highly prevalent disease characterized by hyperglycaemia that
damages the vascular system, leading to micro‐(retinopathy, neuropathy, nephropathy) and …
damages the vascular system, leading to micro‐(retinopathy, neuropathy, nephropathy) and …