Interleukin 6 and aneurysmal subarachnoid hemorrhage. A narrative review

M Simon, A Grote - International Journal of Molecular Sciences, 2021 - mdpi.com
Interleukin 6 (IL-6) is a prominent proinflammatory cytokine. Neuroinflammation in general,
and IL-6 signaling in particular, appear to play a major role in the pathobiology and …

A review of technological innovations leading to modern endovascular brain aneurysm treatment

DC Lauzier, AL Huguenard, AI Srienc, SJ Cler… - Frontiers in …, 2023 - frontiersin.org
Tools and techniques utilized in endovascular brain aneurysm treatment have undergone
rapid evolution in recent decades. These technique and device-level innovations have …

Plasma osteopontin as a biomarker of Alzheimer's disease and vascular cognitive impairment

YL Chai, JR Chong, AR Raquib, X Xu, S Hilal… - Scientific reports, 2021 - nature.com
Cerebrovascular disease (CeVD) and neurodegenerative dementia such as Alzheimer's
disease (AD) are frequently associated comorbidities in the elderly, sharing common risk …

TLR4 (Toll-Like Receptor 4) mediates the development of intracranial aneurysm rupture

K Mitsui, T Ikedo, Y Kamio, H Furukawa, MT Lawton… - …, 2020 - Am Heart Assoc
Inflammation is emerging as a critical factor in the pathophysiology of intracranial aneurysm.
TLR4 (toll-like receptor 4) contributes not only to the innate immune responses but also to …

Secreted phosphoprotein 1 expression in retinal mononuclear phagocytes links murine to human choroidal neovascularization

A Schlecht, P Zhang, J Wolf, A Thien… - Frontiers in Cell and …, 2021 - frontiersin.org
Age-related macular degeneration (AMD) represents the most common cause of blindness
in the elderly in the Western world. An impairment of the outer blood-retina barrier and a …

Preclinical intracranial aneurysm models: a systematic review

F Strange, BE Grüter, J Fandino, S Marbacher - Brain sciences, 2020 - mdpi.com
Intracranial aneurysms (IA) are characterized by weakened cerebral vessel walls that may
lead to rupture and subarachnoid hemorrhage. The mechanisms behind their formation and …

Assessment of serum cytokines and oxidative stress markers in elite athletes reveals unique profiles associated with different sport disciplines

MU Sohail, L Al-Mansoori, H Al-Jaber… - Frontiers in …, 2020 - frontiersin.org
Objectives Circulating cytokines and oxidative stress markers vary in response to different
exercise regimens. This study aims to compare the immune-inflammatory and oxidative …

Upregulation of osteopontin expression via the interaction of macrophages and fibroblasts under IL-1b stimulation

T Shimodaira, K Matsuda, T Uchibori, M Sugano… - Cytokine, 2018 - Elsevier
Background Fibrosis is attributed to dysregulation of tissue-remodeling. In remodeling areas,
fibroblasts and macrophages actively make contact with each other. Osteopontin (OPN) is a …

The link between regional tidal stretch and lung injury during mechanical ventilation

S Yen, M Preissner, E Bennett, S Dubsky… - American Journal of …, 2019 - atsjournals.org
The aim of this study was to assess the association between regional tidal volume (Vt),
regional functional residual capacity (FRC), and the expression of genes linked with …

Monocyte transmodulation: the next novel therapeutic approach in overcoming ischemic stroke?

J Park, JY Chang, JY Kim, JE Lee - Frontiers in neurology, 2020 - frontiersin.org
The immune response following neuroinflammation is a vital element of ischemic stroke
pathophysiology. After the onset of ischemic stroke, a specialized vasculature system that …